Clinical features and treatment of endolymphatic sac tumor.

Endolymphatic sac tumor (ELST) is an extremely rare disease that does not have established clinical guidelines. To provide guidance for the diagnosis and management of ELSTs. We retrospectively reviewed the medical records of patients who were suspected to have a lesion in the location of endolymphatic sac.

β- and β-adrenergic stimulation-induced electrogenic transport by human endolymphatic sac epithelium and its clinical implications.

The endolymphatic sac (ES) is a cystic structure of the inner ear connected to the cochlea and vestibule, which plays a role in regulating ion homeostasis in inner ear fluid. Disruption of ion homeostasis can cause inner ear disorders with hearing loss and dizziness, such as Meniere's disease. Herein, we found, for the first time, functional evidence for the involvement of β- and β-adrenergic receptors in apical electrogenic ion transport by human ES epithelium by using electrophysiological/pharmacological and molecular biological methods, which were dependent on K and Cl ion transport.

Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium.

The endolymphatic sac (ES) is a cystic organ that is a part of the inner ear and is connected to the cochlea and vestibule. The ES is thought to be involved in inner ear ion homeostasis and fluid volume regulation for the maintenance of hearing and balance function. Many ion channels, transporters, and exchangers have been identified in the ES luminal epithelium, mainly in animal studies, but there has been no functional study investigating ion transport using human ES tissue.

Feasiblity of transoral robotic hypopharyngectomy for early-stage hypopharyngeal carcinoma.

Conventional surgical approaches for hypopharyngeal carcinomas have a great risk for developing treatment-related morbidity. To minimize this morbidity, hypopharyngectomy by transoral robotic surgery (TORS) was performed, and the efficacy and feasibility of this procedure were evaluated. TORS was performed using da Vinci Surgical Robot (Intuitive Surgical Inc.