Ophthalmic manifestations have recently been observed in acute and post-acute complications of COVID-19 caused by SARS-CoV-2 infection. Our precious study has shown that host RNA editing is linked to RNA viral infection, yet ocular adenosine to inosine (A-to-I) RNA editing during SARS-CoV-2 infection remains uninvestigated in COVID-19. Herein we used an epitranscriptomic pipeline to analyze 37 samples and investigate A-to-I editing associated with SARS-CoV-2 infection, in five ocular tissue types including the conjunctiva, limbus, cornea, sclera, and retinal organoids.
View Article and Find Full Text PDFA systematic study of nonsequential double ionization (NSDI) of alkaline-earth metal atoms with mid-infrared femtosecond pulses is reported. We find that the measured NSDI yield shows a strong target dependence and it is more suppressed for alkaline-earth metal with higher ionization potential. The observation is attributed to the differences in the recollision induced excitation and ionization cross sections of alkaline-earth metals.
View Article and Find Full Text PDFDiatomic molecules (e.g., O(2)) in an intense laser field exhibit a peculiar suppressed ionization behavior compared to their companion atoms.
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