Basics of particle therapy II: relative biological effectiveness.

In the previous review, the physical aspect of heavy particles, with a focus on the carbon beam was introduced. Particle beam therapy has many potential advantages for cancer treatment without increasing severe side effects in normal tissue, these kinds of radiation have different biologic characteristics and have advantages over using conventional photon beam radiation during treatment. The relative biological effectiveness (RBE) is used for many biological, clinical endpoints among different radiation types and is the only convenient way to transfer the clinical experience in radiotherapy with photons to another type of radiation therapy.

Co-authorship patterns and networks of Korean radiation oncologists.

Purpose: This research aimed to analyze the patterns of co-authorship network among the Korean radiation oncologists and to identify attributing factors for the formation of networks.

Materials And Methods: A total of 1,447 articles including contents of 'Radiation Oncology' and 'Therapeutic Radiology' were searched from the KoreaMed database. The co-authorship was assorted by the author's full name, affiliation and specialties.

Basics of particle therapy I: physics.

With the advance of modern radiation therapy technique, radiation dose conformation and dose distribution have improved dramatically. However, the progress does not completely fulfill the goal of cancer treatment such as improved local control or survival. The discordances with the clinical results are from the biophysical nature of photon, which is the main source of radiation therapy in current field, with the lower linear energy transfer to the target.

Protective effects of hominis placenta hydrolysates on radiation enteropathy in mice.

The aim of this study was to investigate whether the hominis placenta hydrolysates (HPhs) have a protective effect against radiation-induced enteropathies. HPh (1-10 mg kg⁻¹, i.p.

A long term results of external beam radiation therapy in hemophilic arthropathy of the ankle in children.

Bleeding into joint space is critical to develop hemophilic arthropathy. To reduce the frequency of bleeding in the ankle joint of children with hemophilic arthropathy, low dose external beam irradiation was performed for 37 patients. Among them, 35 patients followed-up for longer than 1 yr (median 87 months) were enrolled for analysis.

Analysis of Scientific Publication Networks among Medical Schools in Korea.

Objectives: This research was intended to analyze the special characteristics and structure of social networks among Korean medical schools for the purpose of providing knowledge regarding medical field structure, dynamics, and potential paradigm development.

Methods: A collaborative 12-year data set of 35,469 published articles in the SCOPUS® database was analyzed. Among ISI subcategories, 61 having more than 20 articles were scrutinized.

Adaptive responses induced by low dose radiation in dentate gyrus of rats.

The purpose of this study is to investigate the mechanism of alternative responses to low dose irradiation for neuronal cell proliferation in the dentate gyrus of rats. To determine the effect of a single exposure to radiation, rats were irradiated with a single dose of 0.1, 1, 10 or 20 Gy.

Low dose radiation overcomes diabetes-induced suppression of hippocampal neuronal cell proliferation in rats.

We investigated the effect of low dose radiation on diabetes induced suppression of neurogenesis in the hippocampal dentate gyrus of rat. After 0.01 Gy, 0.

Number of radiation oncologists in Korea, adequate or surplus?

Purpose: The purpose of this research is to discern and address the issues related to the radiation oncology manpower supply and its distribution.

Materials And Methods: The statistical data of the Annual Report of the Korea Central Cancer Registry (KCCR) from 1997 to 2002 and the Annual Report of the Korean Society of Radiation Oncology (KOSTRO) from 1997 to 2004 were used to predict the status of the human resources in 2015. The estimated demand and supply were calculated with the Microsoft Excel program (Microsoft, Redmond, WA).

The application of the Six Sigma program for the quality management of the PACS.

Objective: We implemented a Six Sigma-based quality management program for the PACS to improve the quality of and lessen the necessary resources for its management.

Conclusion: With the Six Sigma-based PACS quality management program, we were able to reduce resource requirements while maintaining quality.

The prognostic effect of VEGF expression in squamous cell carcinoma of the cervix treated with radiation therapy alone.

We investigated the relationship between vascular endothelial growth factor (VEGF) expression and clinical outcome in squamous cell carcinoma of the cervix treated with radiotherapy alone. The immunohistochemical study was performed for forty-two paraffin embedded specimens with anti-VEGF mouse monoclonal antibody. Staining was defined as positive for VEGF when more than 10% of the tumor cells were stained from 500 cells counted.

Comparison of hospital charge prediction models for colorectal cancer patients: neural network vs. decision tree models.

Analysis and prediction of the care charges related to colorectal cancer in Korea are important for the allocation of medical resources and the establishment of medical policies because the incidence and the hospital charges for colorectal cancer are rapidly increasing. But the previous studies based on statistical analysis to predict the hospital charges for patients did not show satisfactory results. Recently, data mining emerges as a new technique to extract knowledge from the huge and diverse medical data.

Clinical Implications of VEGF and p53 Expression in Squamous Cell Carcinoma of the Cervix Treated with Radiation Therapy.

Purpose: The present study was designed to analyze the relationship between vascular endothelial growth factor (VEGF) and p53, and their impact on clinical outcome in squamous cell carcinoma of the cervix treated with radiation therapy.

Materials And Methods: This immunohistochemical study involved 23 patients with available paraffin blocks among 46 patients who were treated during the period from 1994 to 1997 in Eulji University Hospital in Korea. Anti-VEGF mouse monoclonal antibody and DO-7 anti- p53 mouse monoclonal antibody were used as the primary antibodies.