Publications by authors named "Jin Myeong Song"
Theranostics
October 2017
Article Synopsis
- The TM4SF5 protein is a promising target for hepatocellular carcinoma treatment, as it is highly expressed in various cancers and linked to tumor growth.
- Researchers identified and characterized two chimeric antibodies, Ab27 and Ab79, which bind specifically to TM4SF5’s extracellular loop, showing strong binding affinities.
- Both antibodies effectively inhibited cancer cell proliferation and invasion, enhanced sensitivity to anoikis, and reduced tumor growth in a liver cancer model, suggesting their potential as new anti-cancer agents.
