Combining quantitative susceptibility mapping to radiomics in diagnosing Parkinson's disease and assessing cognitive impairment.

Objective: To explore whether magnetic susceptibility value (MSV) and radiomics features of the nigrostriatal system could be used as imaging markers for diagnosing Parkinson's disease (PD) and its related cognitive impairment (CI).

Methods: A total of 104 PD patients and 45 age-sex-matched healthy controls (HCs) underwent quantitative susceptibility mapping (QSM). The former completed Hoehn-Yahr Stage and Montreal Cognitive Assessment (MoCA).

Non-Invasive Estimation of Glioma Mutation and Expression by Histogram Analysis of Dynamic Contrast-Enhanced MRI.

Objectives: To investigate whether glioma isocitrate dehydrogenase () 1 mutation and vascular endothelial growth factor () expression can be estimated by histogram analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).

Methods: Chinese Glioma Genome Atlas (CGGA) database was wined for differential expression of in gliomas with different genotypes. The expression and  genotypes of 56 glioma samples in our hospital were assessed by immunohistochemistry.