Controlled liquid crystal behavior of graphene oxide/single walled carbon nanotube mixtures for continuous multi hole wet spinning.

Liquid-crystalline (LC)-spinning of graphene oxide (GO) is a promising method for producing conducting fibres. However, achieving continuous wet-spinning via a multi-hole spinneret with organic solvent-based spinning dopes remains challenging, primarily because of the limitations in coagulation without ion crosslinking agents, such as Ca and Fe. In this study, we report the colloidal engineering of an LC GO-based spinning dope with highly oxidised single-walled carbon nanotubes (ox-SWCNTs) for continuous multi-hole wet-spinning.

The Role of Cytokines in Perioperative Neurocognitive Disorders: A Review in the Context of Anesthetic Care.

Perioperative neurocognitive disorders (PNDs), including postoperative delirium, delayed neurocognitive recovery, and long-term postoperative neurocognitive disorders, present significant challenges for older patients undergoing surgery. Inflammation is a protective mechanism triggered in response to external pathogens or cellular damage. Historically, the central nervous system (CNS) was considered immunoprivileged due to the presence of the blood-brain barrier (BBB), which serves as a physical barrier preventing systemic inflammatory changes from influencing the CNS.

Effects of epidural dexmedetomidine on patient-controlled epidural analgesia after total knee arthroplasty: a single-center, prospective, double-blind, randomized controlled study.

Objective: To evaluate the impact of adding epidural dexmedetomidine to low-concentration patient-controlled epidural analgesia (PCEA) on pain control and side effects in total knee arthroplasty (TKA).

Methods: In this double-blind study, American Society of Anesthesiologists I to II patients undergoing TKA were assigned to receive 0.125% bupivacaine + fentanyl 4 µg/mL (group R) or 0.

Hydrogen Bond-Driven Hierarchical Assembly of Single-Walled Carbon Nanotubes for Ultrahigh Textile Capacity.

Hydrogen-bond-driven 1D assembly of carbon nanotubes dispersed in organic solvents remains challenging owing to difficulties associated with achieving high oxidation levels and uniform dispersion. Here, we introduced a bioinspired wet-spinning method that utilizes highly oxidized single-walled carbon nanotubes dispersed in organic solvents without superacid or dispersants. By incorporating submicrometer-sized graphene oxide nanosheets, we facilitated the ejection of 1.

Socio-ecological barriers to behavior change-oriented dementia prevention: a qualitative study of healthcare professionals' perspectives.

Objectives: This qualitative study aimed to: (1) identify socio-ecological barriers to behavior change-oriented dementia (AD/ADRD) prevention from the perspectives of healthcare professionals, and (2) propose strategies to address these barriers during a clinical trial for an AD/ADRD prevention program ().

Method: Multidisciplinary healthcare professionals involved in geriatric care ( = 26, experience > 17 years) from diverse clinics within a medical center participated in focus groups. Using the Socio-Ecological Model (SEM), 5 focus groups were conducted to identify individual, interpersonal, institutional, community, and societal barriers.

A Mixed Methods Effectiveness Study of a Peer Support Intervention for Older Adults During the COVID-19 Pandemic: Results of a Randomized Clinical Trial.

Objective: Low-income white older adults and those of color are at greater risk for depression but less likely to receive care. We evaluated the impact of a one-to-one peer support intervention compared to active control delivered by nonpeers for this population.

Design: Mixed methods, single-blind randomized controlled trial.

Preventing Cognitive Decline in Older Latino Adults With HIV Through a Culturally Tailored Health Promotion Intervention: Protocol for a Single-Arm Pilot Trial.

Background: Older Latino adults with HIV are at increased risk for mild cognitive impairment and earlier onset of aging-related cognitive decline. Improvements in cognitive functioning and cognitive outcomes are possible among people with HIV who adopt health promotion behaviors. However, health promotion interventions for older Latino adults with HIV have not been extensively used or widely recognized as viable treatment options.

Effect of Interlayer on Flatness and Adhesion of Aerosol-Deposited Yttrium Oxide Coating.

In this study, YO coating is used as an interlayer between AlO substrate and a ceramic coating; this is in order to minimize the morphological distortion produced by a single deposition of the ceramic coating on the AlO substrate, which is performed using the aerosol method. The interlayer coating, which comprises the YO phase, is deposited on the AlO substrate using an e-beam evaporator. The crystal structure of the powder that was used to process the coating is identified as cubic YO.

Enhancing ketamine anesthesia with midazolam and fentanyl for children's ear surgery: a prospective randomized study.

Background: Myringotomy with tympanostomy tube insertion (MTI) is a superficial surgical procedure used to prevent hearing loss in children with serous otitis media. Intravenous anesthesia, often ketamine, is preferred for this procedure because of its ability to induce sedation without compromising airway reflexes. However, ketamine alone may be insufficient and potentially lead to spontaneous movement during surgery.

Age-related effects of Mycoplasma pneumoniae infection and subsequent asthma exacerbation in children.

Background: Mycoplasma pneumoniae causes community-acquired pneumonia in children and increases asthma risk, but large studies are lacking.

Objective: To assess the link between M. pneumoniae infection and to asthma exacerbation, in children with allergies, and age of infection impact.

Community Health Workers Deliver Mental Health Intervention to Uninsured Latinx in Baltimore: Evaluation and Lessons Learned in a Pilot Program.

Background: Implementation of evidence-based interventions to reduce depression among uninsured Latinx patients who are at high risk of depression are rare.

Objectives: Our goal was to evaluate Strong Minds, a language and culturally tailored, evidence-based intervention adapted from cognitive behavioral therapy (CBT) for mild-moderate depression and anxiety, delivered by community health workers (CHWs) in Spanish to uninsured Latinx immigrants.

Methods: As part of the pilot, 35 participants, recruited from a free community primary care clinic, completed Strong Minds.

Downregulation of the glucose transporter GLUT 1 in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice.

Introduction: Glucose transporter 1 (GLUT1) is essential for glucose transport into the brain and is predominantly expressed in the cerebral microvasculature. Downregulation of GLUT1 precedes the development of cognitive impairment in neurodegenerative conditions. Surgical trauma induces blood-brain barrier (BBB) disruption, neuroinflammation, neuronal mitochondria dysfunction, and acute cognitive impairment.

Evaluation of the lead and chromium removal capabilities of Bacillus subtilis-induced food waste compost-based biomedia.

Food waste compost (FWC) is a sustainable recycling approach employed in soil media, offering extensive advantages to urban areas by promoting resource circulation and effectively managing water pollution. To improve value, Bacillus subtilis (B. subtilis)-induced FWC-based biomedia (BIBM) was produced via a secondary treatment involving selective meso-thermophilic stages.

Addressing chronic pain disparities between Black and White people: a narrative review of socio-ecological determinants.

A 2019 review article modified the socio-ecological model to contextualize pain disparities among different ethnoracial groups; however, the broad scope of this 2019 review necessitates deeper socio-ecological inspection of pain within each ethnoracial group. In this narrative review, we expanded upon this 2019 article by adopting inclusion criteria that would capture a more nuanced spectrum of socio-ecological findings on chronic pain within the Black community. Our search yielded a large, rich body of literature composed of 174 articles that shed further socio-ecological light on how chronic pain within the Black community is influenced by implicit bias among providers, psychological and physical comorbidities, experiences of societal and institutional racism and biomedical distrust, and the interplay among these factors.

Modelling heavy-metal phytoextraction capacities of Helianthus annuus L. and Brassica napus L.

Greenhouse experiments were conducted to test the phytoextraction potential of sunflower (Helianthus annuus L.) and rape (Brassica napus L.) during the initial growth in the heavy metal (i.

The impact of anti-Asian racism on routine activities and mental health among Korean American older adults and their caregivers.

Introduction: Reported anti-Asian discrimination has been on the rise since the COVID-19 pandemic. Nevertheless, limited research addresses the health impact of perceived anti-Asian racism on Asian Americans, especially among older adults, during COVID-19. To address the gap, we examined how the novel coronavirus pandemic affected Korean American older adults, one of the largest Asian subgroups.

The effects of etomidate on expression of high mobility group box 1 via the nuclear factor kappa B pathway in rat model of sepsis.

Etomidate is an anesthetic agent used in hemodynamically unstable patients, but its use has been controversial in septic patients. The response of high-mobility group box 1 (HMGB1), a late-phase lethal cytokine in sepsis, to etomidate has not been reported. This study investigated the effects of etomidate on the expression and release of HMGB1 and the underlying mechanism using a cecal ligation and puncture (CLP) model.

Increasing the Repertoire for Depression Care: Methods and Challenges of a Randomized Controlled Trial of Peer Support for Vulnerable Older Adults.

Objective: Low-income White and older adults of color face barriers to depression care. Our purpose is to describe the methods and challenges encountered during the implementation of a randomized controlled trial to test the effectiveness of a peer support depression care intervention for low-income White and older adults of color during the COVID-19 pandemic.

Methods: Peer Enhanced Depression Care (Peers) is an 8-week community-based intervention that uses peer mentors who are trained and supervised to provide social support and self-care skills to depressed older adults.

Blood Biomarkers in Patients with Parkinson's Disease: A Review in Context of Anesthetic Care.

Parkinson's disease (PD) is the second most common inflammatory neurodegenerative disorder after dementia. Preclinical and epidemiological data strongly suggest that chronic neuroinflammation slowly induces neuronal dysfunction. Activated microglia secrete several neurotoxic substances, such as chemokines and proinflammatory cytokines, which may promote blood-brain barrier (BBB) permeabilization.

Delayed Adverse Events after Procedural Sedation in Pediatric Patients with Hematologic Malignancies.

Background and objectives: Procedural sedation for bone marrow examination (BME) and intrathecal chemotherapy (ITC) is necessary for pediatric patients with hematological malignancies. There has been no report on adverse events after discharge from the recovery room. This retrospective study evaluated the types and incidences of delayed adverse events among pediatric patients scheduled for BME or ITC under deep sedation in a single center for 3 years.

Comparison of the efficacy of erector spinae plane block according to the difference in bupivacaine concentrations for analgesia after laparoscopic cholecystectomy: a retrospective study.

Background: Laparoscopic cholecystectomy (LC) is a noninvasive surgery, but postoperative pain is a major problem. Studies have indicated that erector spinae plane block (ESPB) has an analgesic effect after LC. We aimed to compare the efficacy of different ESPB anesthetic concentrations in pain control in patients with LC.

Development of the Mental Health Peer Support Questionnaire in colleges and vocational schools in Singapore.

Background: A nation-wide mental health peer support initiative was established in college and vocational schools in Singapore. The purpose of this cross-sectional study was to develop and validate a 20-item self-report instrument, the Mental Health Peer Support Questionnaire (MHPSQ), to assess young adults' perceived knowledge and skills in mental health peer support.

Methods: We administered the questionnaire to 102 students who were trained as peer supporters, and 306 students who were not trained as peer supporters (denoted as non-peer supporters), in five college and vocational schools.

Biological Control and Plant Growth Promotion Properties of Volatile Organic Compound-Producing Antagonistic spp.

is environmentally vital due to their plant growth-promoting effects (such as enhancement of nutrients supply, suppression of plant pathogens, and promotion of plant defense). Biogenic volatile organic compounds (VOCs) are diverse chemical substances emitted by spp. The potential role of VOCs in biological control and plant growth promotion has recently been recognized.