Publications by authors named "Jin Hyub Paik"

Background: Intracellular gene transfer (IGT) is a phenomenon in genome evolution that occurs between the nuclear and organellar genomes of plants or between the genomes of different organelles. The majority of the plastid genomes (plastomes) in angiosperms have a conserved structure, but some species exhibit unexpected structural variations.

Results: In this study, we focused on the Ferulinae, which includes Ferula, one of the largest genera in the Apiaceae family.

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As chronic inflammation and oxidative stress cause various diseases in the human body, this study aimed to develop functional materials to prevent inflammation and oxidative stress. This study investigated the biological function and components of L. extract prepared using its leaves and branches (TCE).

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Article Synopsis
  • Researchers isolated 12 new compounds from the MeOH extract of Jacobaea vulgaris, including 11 dihydrostilbenes and one flavanone, along with eight known compounds.
  • Structural analysis of the compounds was done using advanced techniques like NMR spectroscopy and mass spectrometry.
  • Compounds 1 and 3 were found to lower PCSK9 mRNA levels and increase LDLR mRNA levels, indicating they might help reduce cholesterol levels.
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Root extracts of (AT), a shrub native to China, have been shown to have antiviral and antitumor activities, but the anti-obesity effects of AT aerial parts, mainly the leaves and stems, have not been investigated. This study is the first to investigate the anti-obesity effects and molecular mechanism of AT 70% ethanol extract in 3T3-L1 adipocytes and high-fat diet (HFD)-fed C57BL/6J mice. Treatment with AT extract inhibited lipid accumulation in 3T3-L1 cells and decreased the expression of adipogenesis-related genes.

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In this study, we report the first complete plastome sequence of (GenBank acc. no. OP432690).

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Although various hair health medicines have been developed and are used today, additional safe and effective natural hair growth therapies still need to be developed. var. (Hiern) Leenh.

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Background: Chromosome number and genome size changes via dysploidy and polyploidy accompany plant diversification and speciation. Such changes often impact also morphological characters. An excellent system to address the questions of how extensive and structured chromosomal changes within one species complex affect the phenotype is the monocot species complex of Barnardia japonica.

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is widely used pharmacologically in Traditional Chinese Medicine and Ayurvedic medicine as a diuretic, antipyretic, or choleretic and to treat ulcers, snakebites, and edema. Previous studies have shown that phytochemicals from have physiological activities such as anti-inflammatory, anti-tumor, and anti-wrinkle properties. Nevertheless, research on the anti-atopic dermatitis (AD) effect of extract is limited.

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M. Kim. is an endemic species in Korea, and its leaves are distinguished from other taxa of by the leathery texture.

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7--methylluteolin (7-ML) is a flavonoid isolated from the aerial parts of (). We describe the anti-atopic dermatitis (AD) effects of 7-ML in tert-butyl hydroperoxide (tBHP)-induced HepG2 cells and 2,4-dinitrochlorobenzene (DNCB)-induced SKH-1 hairless mice. Results demonstrated that 7-ML dose-dependently inhibited the activation of Nrf2 (nuclear factor-erythroid 2-related factor 2) in tBHP-induced HepG2 cells.

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Lam. (Primulaceae) is known as a medicinal plant with anti-tumor and anti-viral effects. In this study, we reported the first complete chloroplast genome sequence of The total length of the complete chloroplast genome was 152,691 bp, comprising a small-single copy region (SSC) of 17,928 bp, a large-single copy region of 83,811 bp, and a pair of inverted repeat regions of 25,476 bp.

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A novel endophytic bacterial strain, designated GR-TSA-9, was isolated from surface-sterilized grape ( L.). 16S rRNA gene sequence analyses showed that the isolate was grouped within the genus , displaying the highest similarity with DS-18 (97.

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Teijsm. & Binn. (LO) (crape myrtle) has reportedly been used as traditional herbal medicine (THM) in Java, Indonesia.

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(Blume) has been traditionally used to treat inflammatory diseases such as tonsillitis and ulcers throughout Asia, including China, Indonesia, and the Philippines: however, the molecular mechanisms by which exerts its antioxidant and anti-inflammatory properties remain largely unknown. In this study, we analyzed the antioxidant and anti-inflammatory mechanisms of methanol extracts of leaves (MBJ) in vitro and in vivo. MBJ decreased nitric oxide (NO) production and the expression of pro-inflammatory cytokines, including interleukin (IL)-1β, IL-6, and tumor necrosis factor-α, in lipopolysaccharide (LPS)-treated RAW 264.

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Gallic acid and catechin are the most abundant phenolic and flavonoid contents found in all plant extracts. The contents and the bioassay-guided fractionating substances of the (A. Rich) Hochst (Anacardiaceae) fraction played vital roles.

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The genus Disporum Salisb. is widely distributed in East Asia, yet phylogenetically relevant morphological traits useful for differentiating many of the small, perennial, herbaceous species remain poorly described. To address this, leaf, floral, pollen, and orbicule micromorphology of four Korean Disporum species was investigated using light and scanning electron microscopy.

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Plants of the genus are used in Chinese traditional medicine to treat inflammatory diseases, such as arthritis, bronchitis, and pneumonia. The present study was designed to determine whether (Siebold and Zucc.) Maxim.

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Ethnopharmacological Relevance: Callicarpa japonica Thunb., as an herbal medicine has been used for the treatment of inflammatory diseases in China and Korea.

Materials And Methods: Ultra performance liquid chromatography-photodiode array-quadrupole time-of-flight mass spectrometer (UPLC-PDA-QTof MS) was used to detect the major phenylethanoid glycosides in the C.

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(Linn.) Gaertn. () has long been used for the treatment of inflammatory diseases, including liver disease, asthma, rheumatism and earache, in tropical countries throughout America, Asia and Africa.

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Development of anti-inflammatory products remains in high demand due to the incidence of inflammatory diseases, including diabetes, cardiovascular disease, and neurodegenerative diseases. In this study, we examined the potential anti-inflammatory activity of the nutraceutical, (Pierre) Dandy extract (KDE). We evaluated the ability of KDE to inhibit lipopolysaccharide (LPS)-induced inflammatory markers, including nitric oxide (NO), nuclear factor kappa-B, and mitogen-activated protein kinases, in RAW 264.

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Physalis peruviana L. (PP) is well known for its various properties, including its antioxidant property. In our previous study, the protective effects of PP against cigarette smoke‑induced airway inflammation were confirmed.

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Ethnopharmacological Relevance: The ethnobotanical survey was carried out in the Bac Huong Hoa Nature Reserve (BHHNR), Vietnam. The Van Kieu ethnic group, the inhabitant of Nature Reserve, is rich in knowledge about the medicinal plants found in the Nature Reserve. However, their knowledge is less documented.

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Article Synopsis
  • Rhododendron album Blume (RA) is traditionally used as an herbal medicine with anti-inflammatory properties, particularly for allergic diseases.
  • A study investigated how a methanol extract of RA (RAME) affects inflammation in human skin cells stimulated by TNF-α and IFN-γ, focusing on chemokines and cytokines' production.
  • Results showed that RAME significantly reduced the expression of pro-inflammatory molecules by inhibiting the NF-κB and JAK/STAT pathways, suggesting its potential use in treating atopic dermatitis.
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