Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Insomnia Disorder: A Randomized Clinical Trial.

Importance: Evidence from randomized clinical trials of transcutaneous auricular vagus nerve stimulation (taVNS) for chronic insomnia disorder is lacking.

Objective: To evaluate the efficacy and safety of taVNS for chronic insomnia compared with the sham taVNS.

Design, Setting, And Participants: This randomized clinical trial was conducted from October 2021 to December 2022 at a single center in Beijing, China.

Decoction derived from L. bulbs and Sojae Semen Praeparatum alleviates wind-cold-type common cold Nrf2/HO-1 pathway and modulation of level.

Background: Cong-Chi decoction (CCD) is made using L. (shallot) bulbs and Sojae Semen Praeparatum (SSP). Shallot bulbs and SSP are both used regularly in traditional Chinese medicine; however, there are no recent pharmacological studies on their synergistic effects.

's experience in treatment of allergic rhinitis by acupuncture-moxibustion at "band-like function zone of back- points".

The paper introduces professor 's clinical experience in treatment of allergic rhinitis by acupuncture and moxibustion. Allergic rhinitis is closely associated with the dysfunction of lung, spleen and kidney. Based on the theory of "band-like function zone of back- points", the main acupoints related to the affected organs are selected to enhance the conductivity, regulate function and strengthen the antipathogenic specially; and the supplementary points are combined in terms of syndrome/pattern differentiation so that both symptoms and root causes of the disease can be treated simultaneously, the symptoms of allergic rhinitis be attenuated and the recurrence be prevented.

Application of clinical value assessment of treatment protocols in guideline development: taking the WFAS as an example.

To enhance the clinical applicability of guidelines and provide more effective guidance for clinical practice, a clinical value assessment was conducted during the development of the World Federation of Acupuncture-Moxibustion Societies (WFAS) , which involved the evaluation of 59 acupuncture and moxibustion treatment protocols from randomized controlled trials (RCTs). This article introduced the methodology, content and results of the clinical value assessment of RCT-based acupuncture and moxibustion treatment protocols, which involved the integration of historical and contemporary medical evidence and expert consensus. It served as a methodological reference for the future development of acupuncture and moxibustion clinical practice guidelines.

Baicalin Relieves Airway Inflammation in COPD by Inhibiting miR-125a.

To investigate the effects of Baicalin on the apoptosis of human bronchial epithelial cells (16HBE) induced by cigarette smoke extract (CSE) and the release of inflammatory factors, and to clarify its possible mechanism. CSE was used to treat 16HBE cells and construct COPD cell model. The activity of 16HBE cells was detected by CCK-8 and BrdU.

Effectiveness of Acupuncture for Prophylactic Treatment of Migraine: A Systematic Review and Bayesian Network Meta-Analysis.

It is aimed to evaluate the effectiveness and provide evidence-based medical support for acupuncture as a prophylactic treatment for migraines. Randomized controlled trials (RCTs) from inception to April 2022 are included in 14 databases. Pairwise meta-analysis is conducted using STATA software V14.

[Problems in randomized controlled trial on acupuncture and moxibustion for migraine in the development of international standard of : ].

Regarding the development of international standard of : the existing problems of the design and methodology of randomized controlled trial (RCT) on acupuncture and moxibustion for migraine were summarized in views of participant, intervention, control, outcome and study design. Four directions need to be further explored, (1) research of adolescent migraine, special subtype of migraine and migraine in a special population; (2) research of the immediate analgesic effect of acupuncture and moxibuation at the attack stage of migraine and the therapeutic effect of migraine at each stage; (3) research on safety and health economics; (4) clinical trial registration of acupuncture and moxibustion. In study, the target population should be further determined and specialized, the diagnosis criteria of western medicine and traditional Chinese medicine be generalized and concentrated, the staging and type division of disease be accurate, the intervention procedure be integrated, the control design be rationalized, the outcomes be validated, and the description of randomization and blinding be clarified.

Investigation and Analysis of the Key Objectives of WFAS "Technical Specifications of Acupuncture and Moxibustion: General Rules for the Drafting".

Objective: To determine the key objectives of WFAS "Technical Specifications of Acupuncture and Moxibustion: General Rules for the Drafting" (hereinafter referred to as General Rules).

Methods: From the medical institutions, colleges, and scientific research organizations at major levels in China and overseas, leading researchers and experts in the field of acupuncture-moxibustion standardization, as well as some experienced foreign specialists in acupuncture-moxibustion, were selected as the respondents. The questionnaire was prepared by using the website of Questionnaire Star, and 60 links of the questionnaire were sent out through e-mail.

[Analysis of the results of international demand survey on ].

The survey is conducted prior to the development of international standard, - () to determine the international demand. The survey includes 5 aspects, i.e.

[Analysis on development necessity and key points for of international industry organization standard].

This paper analyzes the development necessity of a series of international technical specification of acupuncture-moxibustion from three aspects, the development status of global , providing technical support for acupuncture-moxibustion legislation and assisting standardized acupuncture-moxibustion research. The necessity of giving priority to the development of WFAS's ( for short) in the series of standards is discussed from filling the field gap and following the international practice. The key points should be paid attention to in the development process of are summarized，such as improving practicality based on international perspective, enhancing authority by following international rules, improving international applicability by forming a professional team and ensuring high quality and objective neutrality of the .

[Triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) for trunk-sciatica].

Objective: To compared the clinical effect between triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) and triple needling combined with electroacupuncture at Huantiao (GB 30) for trunk-sciatica.

Methods: A total of 56 patients with trunk-sciatica were randomized into a triple needling combined with thermo-electroacupuncture group and a triple needling combined with electroacupuncture group, 28 cases in each group. In the triple needling combined with thermo-electroacupuncture group, triple needling combined with thermo-electroacupuncture at Huantiao (GB 30) was applied.

[Transformation of the domestic standard (: ) to international standard: in the perspective of the differences in clinical questions].

Through analyzing the differences in the clinical questions of : () between the domestic standard and international standard (under development), the specific issues are determined in the transformation from domestic standard to international one. Taking acupuncture practitioners as investigation object, by means of the survey, the basic information and clinical questions were investigated. The survey results show that the following aspects should be supplemented in terms of the international requirements during the development of this international : suitable patient population, applicable types of disease, the optimal intervention time of acupuncture for migraine, common methods in treatment as well as the other involved health problems.

[Needle-embedding treatment for hemifacial spasm: research progress].

The articles regarding needle-embedding treatment for hemifacial spasm published before September 30, 2019 were searched from SinoMed, Wanfang, CNKI, VIP and PubMed database, and were analyzed and summarized from treatment methods, acupoint selection, stage differentiation and action mechanism. As a result, 45 Chinese articles were obtained. The needle-embedding treatment was divided into intradermal needling and acupoint thread-embedding; the top five acupoints were Sibai (ST 2), Taiyang (EX-HN 5), Dicang (ST 4), Jiache (ST 6) and spasm trigger points.

[Bibliometric analysis of refractory facial paralysis based on CNKI database].

The current development situation and the hotspot of the relevant research on refractory facial paralysis are explored. The articles on refractory facial paralysis are retrieved from CNKI database. The bibliographic items co-occurrence matrix builder (BICOMB) 2.

[Analysis on international demand investigation for technical specification of acupuncture- moxibustionthe and its general rules of drafting].

The electronic questionnaire was adopted to survey the international demand on - ( for short) to explore the potential problems during the application and provide the evidence for the development of international standard of . A total of 102 valid questionnaires were collected from 18 countries and regions. The priority of the demand for international standard on the technical specification of acupuncture-moxibustion is filiform needle, moxibustion, electroacupuncture, cupping, auricular acupuncture, scalp acupuncture and scraping.

[Research status of the effect mechanism on catgut-point embedding therapy].

This paper aims to review the research status of the effect mechanism of catgut-embedding therapy. The literature was retrieved from China Academic Journal Network Publishing Database with the keywords as "catgut-point embedding" "embedding", dated from the database establishment to December 2015. Totally, over 5 000 papers had been collected.

[Efficacy on primary trigeminal neuralgia treated with triple puncture technique and electroacupuncture at trigger points].

Objective: To compare the clinical efficacy on primary trigeminal neuralgia between the combined therapy of electroacupuncture and triple puncture and the routine electroacupuncture therapy.

Methods: Thirty-six patients of primary trigeminal neuralgia were randomly assigned into an electroacupuncture and triple puncture group (group A) and a routine electroacupuncture group (group B), 18 cases in each one. In the group A, the triple puncture technique was used at the trigger points (the positive reactive points to trigger facial pain) and stimulated with electricity.

[Influence of drought on leaf photosynthetic capacity and root growth of soybeans at grain filling stage].

A drought-resistant soybean cultivar Jinda 70 and a drought-sensitive soybean cultivar Jindou 26 were taken as test materials. At the grain filling stage, the cultivars were subject to three water treatments including sufficient water supply, light drought stress, and severe drought stress by using pot experiments for research on influence of drought on leaf photosynthetic capacity and root growth of soybeans. The results showed that as the degree of drought stress was aggravated, all of the indices including leaf area, chlorophyll content, net photosynthetic rates (Pn), stomatal conductance (g(s)), transpiration rate (Tr), intercellular CO2 concentration (Ci), plant mass, plant height, seed yield, and harvest index in the two cultivars declined.

[Questionnaire investigation on cost-effectiveness analysis of acupuncture for migraine].

Objective: By using questionnaire method to understand the evaluation regarding cost-effectiveness of acupuncture for migraine in both doctors and patients.

Methods: By using questionnaire method, questionnaires for doctors and patients were made respectively; by using network platform, two sets of questionnaires were publicly released, which were filled in online. The results were real-time background collected and then analyzed.