Publications by authors named "Jin Eop Kim"
Article Synopsis
- The study investigates HL156A, a potent AMPK activator, as a potential treatment for autosomal dominant polycystic kidney disease (ADPKD), which is commonly associated with cyst growth in kidneys.
- In laboratory tests, HL156A significantly inhibited the proliferation of renal cyst cells, showing a 25% reduction in cell viability at concentrations as low as 5 µM, while metformin had no effect.
- In mouse models, HL156A demonstrated its ability to effectively reduce both the number and size of cysts, improve kidney function, and modify key cellular signaling pathways related to cyst growth.
Renal Replacement Therapy For Elderly Patients with ESKD Through Shared Decision-Making.
Electrolyte Blood Press
June 2023
The incidence and prevalence of end-stage kidney disease (ESKD) in Korea are increasing, and ESKD constitutes a very important medical and social issue. Elderly dialysis patients have the highest risk of early mortality within 3 months after initiating dialysis, and geriatric syndromes such as aging, frailty, functional impairment, and cognitive impairment are crucial for the prognosis of elderly patients. Shared decision-making (SDM) is an approach through which clinicians and patients can achieve informed preferences, thereby yielding better clinical outcomes and quality of life.
View Article and Find Full Text PDFA 47-year-old female previously diagnosed with ADPKD visited the hospital due to sudden pain in her upper abdomen and back. Esophagogastroduodenoscopy, contrast-enhanced abdominal computed tomography (CT), and CT angiography identified an esophageal artery pseudoaneurysm and hematoma in the esophagus. Urgent angiography and embolization were performed.
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