Publications by authors named "Jimmy Hinson"
Article Synopsis
- * A model was trained on the Komodo US claims database to find symptomatic patients with AATD, and clinical experts validated that a significant portion of high-probability candidates should undergo testing for the disease.
- * The optimized machine-learning model successfully identified symptomatic patients with probable AATD and revealed unique patterns in the medical histories of patients with AATD compared to those with similar conditions, enhancing understanding of their diagnostic journeys.
Background: Prucalopride is a selective, high-affinity serotonin type 4 receptor agonist approved for the treatment of chronic idiopathic constipation (CIC) in adults. We investigated the impact of prucalopride cessation and re-treatment on efficacy and safety.
Methods: Data were from two randomized controlled trials in adults with CIC.
Introduction: This post hoc analysis evaluated the effect of prucalopride on abdominal bloating in participants with chronic idiopathic constipation (CIC) who had moderate to very severe bloating at baseline.
Methods: Data from 6 phase 3/4 studies of prucalopride in participants with CIC were pooled. Abdominal bloating was assessed weekly using a 5-point scale (0-4).