Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) as a potent anti-angiogenesis agent for endometriosis in mice.

Green tea epigallocatechin-3-gallate (EGCG) can inhibit angiogenesis and development of an experimental endometriosis model in mice, but it suffers from poor bioavailability. A prodrug of EGCG (pro-EGCG, EGCG octaacetate) is utilized to enhance the stability and bioavailability of EGCG in vivo. In this study, the potential of pro-EGCG as a potent anti-angiogenesis agent for endometriosis in mice was investigated.

Dose-dependent enhancement of spinal fusion in rats with teriparatide (PTH[1-34]).

Study Design: Controlled animal experiments.

Objective: To test the dose and efficacy of teriparatide in a rat spinal fusion model.

Summary Of Background Data: Teriparatide was shown to enhance spinal fusion in rats and rabbits previously, but the dose-dependent effect of teriparatide in spinal fusion in rats was not well characterized.

The evaluation of the nurses' work performance after nursing information system implementation in one medical center in Taiwan.

The purpose of this study was to evaluate the nurses' work performance before and after implementation of two nursing information subsystems: Patient Admission Nursing Documentation(PAND) and Physical Examination Documentation(PED) in 2351 beds medical center in Taiwan. Nurses' work performance was measured by time observation. The results of research showed that PAND increased the nurses' work performance 19.

Action of 5-HT3 receptor antagonists and dexamethasone to modify cisplatin-induced emesis in Suncus murinus (house musk shrew).

Ondansetron (1-3 mg/kg), granisetron (0.3-1 mg/kg) and dexamethasone (0.3-1 mg/kg), administered at 12-h intervals, were investigated for their potential to prevent cisplatin (30 mg/kg, i.