Publications by authors named "Jim Zhongning Chen"
Article Synopsis
- A study examined the relationship between Doppler ultrasound-derived mean fenestration gradient (mFG) and direct measurements of transpulmonary gradient (TPG) in patients who underwent the Fontan procedure, a common surgical treatment for single ventricle anatomy.
- The research included 59 patients from a single center between 2000 and 2022 and found that mFG and TPG were weakly correlated, indicating that mFG can only explain about 38% of the variance in TPG measurements.
- The study suggests that while mFG offers a non-invasive way to assess TPG, healthcare providers should be cautious and consider direct catheterization for accurate evaluations in Fontan patients.
Biomarkers play a crucial role in the diagnosis, prognosis, and therapeutics of cancer. We use biomarkers to identify, image, monitor, and target cancer. In many respects, the discovery of pertinent biomarkers that distinguish fulminant from indolent neoplasms and sensitive from refractory malignancies would be a holy grail of cancer research and therapy.
View Article and Find Full Text PDFDoxorubicin (DOX)-induced cardiotoxicity is a major limitation to its clinical application. Cardiotoxicity of DOX is dose-dependent that begins with the first dose. Oxidative stress and inflammation are involved in DOX-related cardiotoxicity.
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