Management of Acute Hypertensive Heart Failure.

Heart failure presents a particularly difficult public health challenge. Of the heart failure presentations, acute hypertensive heart failure represents a distinct clinical phenotype and is characterized by sudden-onset systemic hypertension and pulmonary edema. The pathophysiology of acute hypertensive heart failure is primarily driven by an abnormal ventricular-vascular relationship, and the medical management is aimed at improving this relationship.

Iron, inflammation and atherosclerosis risk in men vs. perimenopausal women.

Objective: Age at first atherosclerotic event is typically older for women vs. men; monthly iron loss has been postulated to contribute to this advantage. We investigated the relationship between an MRI-based arterial wall biomarker and the serum inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) in perimenopausal women vs.