Publications by authors named "Jim Thigpen"

Epilepsy affects approximately 1 percent of the population and roughly 1 million women of childbearing age. Estimates suggest that 0.3-0.

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The novel coronavirus disease 2019 (COVID-19), appeared in the United States over 1 year ago. This virus has a wide range of presentations, from being asymptomatic to causing severe acute respiratory syndrome, which can lead to death. It has led to a worldwide effort to find effective treatments, from repurposed medications to new discoveries, as well as the push to develop effective vaccines.

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Cytomegalovirus (CMV) was first identified in the 1950s and noted to cause newborn disease in the 1960s. It is now known to be the most common cause of congenital infection in the world, leading to various central nervous system sequelae, the most common being hearing loss. Cytomegalovirus is a ubiquitous pathogen that affects nearly 30,000 infants annually in the United States, leading to 3,000-4,000 cases of hearing loss.

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Purpose: The stability of sildenafil in combination with heparin and dopamine was evaluated.

Methods: A stability-indicating high-performance liquid chromatography method with ultraviolet detection was developed for sildenafil citrate and validated. The method was applied to the investigation of sildenafil alone, sildenafil with heparin, sildenafil with dopamine, and sildenafil with heparin and with dopamine, all in 5% dextrose injection at room temperature and under refrigeration for 30 days.

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Objective: To determine if the frequency of self-testing of course material prior to actual examination improves examination scores, regardless of the actual scores on the self-testing.

Methods: Practice quizzes were randomly generated from a total of 1342 multiple-choice questions in pathophysiology and made available online for student self-testing. Intercorrelations, 2-way repeated measures ANOVA with post hoc tests, and 2-group comparisons following rank ordering, were conducted.

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Objectives: To determine if student self-testing improves performance during a doctor of pharmacy course.

Methods: Students were given access to online quizzes with a large pool of randomly selected questions specific to upcoming examination content. Quizzes were electronically scored immediately upon completion and students were provided corrective feedback.

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Article Synopsis
  • The study aimed to assess the stability of a generic lansoprazole suspension in sodium bicarbonate stored at room temperature versus refrigerated.
  • During a month-long analysis, the room temperature samples lost over 10% of the active ingredient in just 48 hours, while refrigerated samples remained stable for up to 7 days with no significant pH difference affecting stability.
  • The findings recommend that the compounded lansoprazole suspension should not be stored over 48 hours at room temperature or more than 7 days in the refrigerator, indicating an earlier expiration than previously suggested.
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