Efficacy and Cardiovascular Safety of Meglitinides.

Meglitinides are a group of oral hypoglycemic medications currently approved for the treatment of type 2 diabetes mellitus (T2DM). Two meglitinide molecules, Repaglinide and Nateglinide, are presently in use. Repaglinide is preferred because of its superior glycemic efficacy.

Clinical Presentation, Treatment, and Outcome of Acromegaly in the United Arab Emirates.

Objectives: We sought to ascertain the clinical characteristics and control rate of acromegaly in the UAE.

Methods: We conducted a multicenter retrospective analysis of all patients presenting with acromegaly to six endocrine centers in the UAE between November 2010 and December 2018. Demographic, clinical, biochemical, and radiologic data were collected.

The effects of inhaled corticosteroids on growth in children.

Inhaled corticosteroids (ICS) are recommended as the first-line therapy for children with persistent asthma. These agents are particularly effective in reducing underlying airway inflammation, improving lung function, decreasing airway hyper-reactivity, and reducing intensity of symptoms in asthmatics. Chronic diseases, such as asthma, have growth-suppressing effects independent of the treatment, which inevitably complicates growth studies.

Etiology and clinical profile of patients with Cushing's syndrome: A single center experience.

Background: There is little published literature on the profile of patients with Cushing's syndrome (CS) from India. The aim of this study was to compile data of CS patients treated at this hospital.

Materials And Methods: Patients referred to the endocrine services of this hospital for diagnosis/treatment of CS from January 1985 to July 2012 were the subjects for this study.

Cushing's disease: results of treatment and factors affecting outcome.

Objective: To analyze the therapeutic results of intervention and the factors affecting the outcome of patients with Cushing's disease (CD) cared for at the All Indian Institute of Medical Science (AIIMS), New Delhi.

Design: Patients with Cushing's disease treated at a teritiary care centre from January 2000 to December 2009 were prospectively studied.

Results: Ninety-seven patients received treatment for CD during this period.

Gender identity of children and young adults with 5alpha-reductase deficiency.

Male pseudohermaphroditism (46,XY DSD) due to 5alpha-reductase deficiency has been recognized for the last few decades. There is scant literature on this entity in India. We compiled data on five patients with this disorder.

Partial duplication of the hypophysis in adult patients: report of 2 cases.

Complete duplication of the pituitary gland is an extremely rare condition which is associated with a wide range of anomalies. An incomplete duplication affecting only the anterior pituitary gland or the pituitary stalk has not been described so far. We report 2 such cases of partial duplication of the hypophysis and briefly review the literature.

Medullary thyroid carcinoma: a 20-year experience from a centre in South India.

Background: Management of medullary thyroid carcinoma (MTC) remains controversial despite many advances over the past five decades. We attempt to review the presentation, management and prognosis of MTC at our institution over the last two decades.

Methods: We conducted a retrospective review of the records of 40 patients with MTC over a period of 20 years.