Publications by authors named "Jim Burrow"

Article Synopsis
  • Cerebral venous thrombosis (CVT) associated with vaccine-induced immune thrombotic thrombocytopenia (VITT) has high in-hospital mortality, but outcomes are better for those who survive hospitalization after SARS-CoV-2 vaccination.
  • In a study of 107 CVT-VITT cases, 40% died during initial hospitalization, but of the 60 patients who survived, 88% achieved functional independence after a median follow-up of 150 days.
  • No new thrombotic events were reported post-discharge, and only one case of major bleeding occurred, indicating a generally positive prognosis for survivors.
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Article Synopsis
  • The study investigates the treatment of cerebral venous thrombosis (CVT) caused by vaccine-induced immune thrombotic thrombocytopenia (VITT) following adenovirus-based COVID-19 vaccinations.
  • Researchers analyzed data from 99 patients across 17 countries to assess adherence to recommended treatments, including immunomodulation and avoiding certain anticoagulants.
  • While overall adherence to these treatment guidelines did not significantly impact mortality, patients who received immunomodulation showed lower mortality rates compared to those who did not.
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Article Synopsis
  • - The study focuses on patients who developed cerebral venous sinus thrombosis (CVST) after receiving SARS-CoV-2 vaccines, specifically ChAdOx1 (Oxford-AstraZeneca) and Ad26.COV2.S (Johnson & Johnson), particularly looking at those with thrombosis with thrombocytopenia syndrome (TTS) versus those without.
  • - Data was gathered from an international registry from 81 hospitals spanning 19 countries, highlighting the clinical characteristics and mortality rates of patients with CVST in relation to their vaccination status.
  • - Of 116 postvaccination CVST patients, 67.2% had TTS, predominantly after the ChAdOx1 vaccine, with a notable percentage of female patients and
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Murray Valley encephalitis virus (MVEV) is a mosquito-borne virus endemic to Australia and New Guinea. Encephalitis due to MVEV is potentially devastating, and no therapeutic interventions of proven value exist. Prevention relies largely on personal protective measures against mosquito bites.

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