Publications by authors named "Jillian Lamb"
Use of dupilumab for recalcitrant bullous pemphigoid: A case report.
SAGE Open Med Case Rep
August 2024
Article Synopsis
- Bullous pemphigoid is an autoimmune blistering disease primarily affecting older adults, with common treatments being corticosteroids and immunosuppressants.
- These first-line therapies can have safety concerns, which may limit their use.
- A case report highlights the successful use of dupilumab, a monoclonal antibody, in treating a patient with resistant bullous pemphigoid.
Aims: We investigated whether patient choice of follow-up type improves health-related quality of life (HrQOL) and follow-up attendance in women who have undergone large loop excision of the transformation zone (LLETZ) for cervical intraepithelial neoplasia grade 2 to 3 (CIN 2-3).
Methods: A three-armed randomised controlled trial including women with newly diagnosed CIN 2-3 post-LLETZ treatment was performed. Consenting women were randomised (1:1:1) to either: (a) colposcopy review at the hospital, (b) follow-up with high-risk human papilloma virus (HrHPV) and smear test in the community or (c) a choice of the aforementioned follow-up options, six months post-treatment.
Initial observation of CIN2 does not appear to reduce quality of life in women under 25 years of age.
Aust N Z J Obstet Gynaecol
August 2017
Background: Although the patient perspective is implicit in the practice of medicine, research evaluating this remains scarce. In a climate where clinicians and policy-makers constantly strive to achieve more patient-centred models of care, this omission warrants attention.
Aim: To assess health-related quality of life (HrQoL) in women under 25 years of age with cervical intra-epithelial neoplasia grade 2 (CIN2) receiving conservative management (colposcopy follow-up, with treatment if necessary) compared with those receiving immediate excisional treatment with large loop excision of the transformation zone (LLETZ).