Publications by authors named "Jillian K Chan"
Article Synopsis
- Spinal cord atrophy is an important measure for monitoring Multiple Sclerosis (MS), but it's less commonly imaged compared to the brain due to challenges in imaging techniques and time constraints.* -
- The study aimed to compare the spinal cord measurements from regular brain MRI scans with dedicated spinal cord MRI scans in both healthy individuals and those with MS.* -
- The results showed a strong correlation between spinal cord measurements from both imaging methods, suggesting that cross-sectional area from brain imaging can effectively estimate spinal cord atrophy.*
Background: Patients with multiple sclerosis (MS) experience progressive thinning in optical coherence tomography (OCT) measures of neuroaxonal structure regardless of optic neuritis history. Few prospective studies have investigated the effects of disease-modifying therapies on neuroaxonal degeneration in the retina. Alemtuzumab is a monoclonal antibody shown to be superior to interferon β-1a in treating relapsing-remitting MS (RRMS).
View Article and Find Full Text PDFAdvanced imaging findings in progressive solitary sclerosis: a single lesion or a global disease?
Mult Scler J Exp Transl Clin
January 2019
Background: Progressive solitary sclerosis is a unifocal demyelinating disease recently proposed as a possible multiple sclerosis variant.
Objective: To compare myelin content and brain metabolite ratio qualitatively in the normal-appearing white matter of progressive solitary sclerosis cases compared to multiple sclerosis and healthy control participants.
Methods: Case report.
Case of alemtuzumab-related alopecia areata management in MS.
Neurol Neuroimmunol Neuroinflamm
January 2019