Publications by authors named "Jillian De Malmanche"
Article Synopsis
- * It explores the mechanisms behind prothrombotic conditions associated with ITP and discusses possible treatment options.
- * The balance between using antiplatelet medications and eltrombopag for effective management is a key focus of the discussion.
Background: Hereditary haemorrhagic telangiectasia (HHT) is a rare genetic vascular disorder which is characterised by the development of arteriovenous malformations and telangiectasias. A key clinical manifestation is recurrent epistaxis. This study examined the impact of a dedicated HHT clinic in a major Australian tertiary hospital on epistaxis symptoms and subjective quality of life.
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- - Thrombotic microangiopathy (TMA) is a complex condition that can arise after kidney transplants due to various factors like medication, rejection, infections, genetic mutations, and autoimmune issues.
- - A 52-year-old male renal transplant patient complicated the situation by developing severe medical conditions, including microangiopathic hemolytic anemia and major deep vein thrombosis, with no improvement from standard treatments like calcineurin inhibitor withdrawal or eculizumab.
- - Ultimately, a bone marrow biopsy led to a diagnosis of metastatic adenocarcinoma, illustrating a rare case where TMA is linked to cancer in a kidney transplant recipient, emphasizing the importance of early detection for effective treatment through chemotherapy.
Pure red cell aplasia is an uncommon cause of anaemia rarely associated with thymoma. A combination of immunosuppressive therapy and thymectomy offers a potential cure. Thymectomy alone rarely results in anaemia resolution.
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