Seven-day storage of single-donor platelets: recovery and survival in an autologous transfusion study.

Background: Bacterial screening may effectively reduce the morbidity and mortality risk associated with extended storage of platelets. Platelet viability then becomes the primary determinant of acceptable storage time. This study evaluates the effectiveness of platelets stored in plasma for 7 days.

Production of pathogen-inactivated RBC concentrates using PEN110 chemistry: a Phase I clinical study.

Background: Despite extensive reductions in risk, donor selection and testing cannot eliminate pathogen transmission. The objective of this study was to evaluate clinically the viability of pathogen-inactivated RBCs.

Study Design And Methods: Twelve healthy subjects each donated two units of blood that were handled as additive system control units or were inactivated using the PEN110 process (INACTINE, V.