Publications by authors named "Jill B Fiedler-Kelly"
Br J Clin Pharmacol
December 2019
Article Synopsis
- Fremanezumab is a monoclonal antibody designed to prevent migraines in adults, with its pharmacokinetics (how the drug moves through the body) analyzed in various patient groups.
- * The study employed nonlinear mixed effects modeling to evaluate data from 7 clinical trials focused on different dosing methods, ensuring comprehensive assessment of how factors like body weight affect drug clearance.
- * The findings established a reliable model for fremanezumab's pharmacokinetics, indicating that factors like weight impact drug distribution, while other elements such as age and sex showed no significant influence, aiding future research on drug efficacy and safety.
