Procyanidin B2 targeted CCR7 expression to inhibit the senescence-associated secretory phenotype through the NF-κB pathway to promote osteogenic differentiation of periodontal ligament stem cells in periodontitis.

Periodontitis is recognized as a chronic inflammatory disease, with aging emerging as a significant risk factor. Cellular senescence plays a crucial role in the biological process of aging. The senescence-associated secretory phenotype (SASP) is characterized by a series of pro-inflammatory factors, chemokines, and proteases, which are hallmark characteristics of senescent cells.

[Effect of different cleaning methods on bond strength and surface wettability of high translucency zirconia].

Purpose: To study the effect of different cleaning methods on the shear bond strength of self-adhesive resin cement to saliva-contaminated high translucency zirconia and surface wettability.

Methods: Eighty zirconia specimens were randomly divided into 5 groups (n=16), i.e.

Anthocyanins-natural pigment of colored rice bran: Composition and biological activities.

Rice by-products are a potential source of various bioactive substances with great processing potential, which are receiving increasing attention. Among them, rice bran is a by-product of rice milling, with high nutritional value and health benefits. Colored rice bran contains a large amount of anthocyanins responsible for color and bioactivities.

[Effect of different dentin cleaning agents on the bond strength of self-adhesive resin cement to dentin].

Objective: This study aims to evaluate the bond strength of a self-adhesive resin cement to dentin by ethylene diamine tetraacetic acid (EDTA) and NaClO.

Methods: Twenty-seven freshly extracted non-carious human premolars were prepared to expose the buccal dentin and randomly divided into three groups: control group (A group), EDTA group (B group) and NaClO group (C group). All teeth were bonded to dentin using a self-adhesive resin cement after the teeth in the A group were processed with distilled water.

[Assessment of occlusal vertical dimension using angles: a pilot study].

Objective: This study aims to identify highly accurate quantitative methods for evaluating the occlusal vertical dimension by using cephalometric radiographs to analyze the craniofacial hard tissue landmarks in 30 cases with normal occlusions.

Methods: A total of 30 subjects with normal occlusions and aged between 20 and 30 years old were included in the study. Cephalometric radiographs were obtained and analyzed using the Winceph 8.

[Clinical evaluation of denture adhesive combined with oral wetting spray on satisfaction of complete denture in xerostomia patients].

Purpose: The purpose of this study is to investigate the effect of denture adhesive and oral wetting spray on the satisfaction of wearing complete denture in xerostomia patients.

Methods: Ten edentulous patients who suffered from deficient residual alveolar ridge and xerostomia with poor retention and stability of complete dentures or mandibular complete dentures were employed to assess the differences of satisfaction after use of denture adhesive in their dry oral cavity for 1 week, and use of denture adhesive combined with oral wetting spray for 1 month, 3 months and 6 months by using satisfaction questionnaire. The statistical analysis was carried out with SPSS17.