Salivary Oxidative Stress, Total Protein, Iron and pH in Children with β-Thalassemia Major and their Correlation with Dental Caries.

Statement Of The Problem: Iron overload in β-thalassemia major leads to oxidative damage to tissues, which may have an important role in the onset and progression of oral diseases.

Purpose: The aim of this study was to evaluate the salivary oxidative stress indicators, total protein, iron, and pH in children with β-thalassemia major and their relationship with the status of dental caries in comparison with healthy children.

Materials And Method: In this case-control study, 68 β-thalassemia major and healthy children, who were age- and sex matched, were selected.

Neurologic manifestations in patients with COVID-19: A case report.

Background: There are very few reports about the neurological complications of COVID-19. We describe two COVID-19 patients with neurologic presentations.

Case Presentation: Herein we present neurological manifestations in 2 hospitalized patients with COVID-19.

Vital role of chest CT in diagnosis of coronavirus disease 2019 (COVID-19).

In December 2019, a new virus called coronavirus disease 2019 (COVID-19) causing severe acute respiratory syndrome emerged in Wuhan, China, and rapidly spread to other areas of China and other regions of the world. Since it was a discovery, COVID-19 has spread to several countries and to this date, affecting about 2,329,651 people and caused about 160,721 deaths. Since most COVID-19 infected cases were diagnosed with pneumonia and characteristic chest computed tomography (CT) scan patterns, radiological examinations have become an important tool in early diagnosis.

HBS Ag seroclearance and seroconversion time in Patients with chronic hepatitis B Infection.

Background: Hepatitis B Surface antigen (HBsAg) seroclearance and seroconversion (development of antibodies against HBsAg) can increases the survival of Chronic hepatitis B (CHB) patients. The aim of this study was to determine the percentage and timing of HBsAg seroclearance and seroconversion in patients with chronic hepatitis B infection.

Methods: 1026 patients with CHB infection who referred to a private clinic were included.

Clinical and laboratory findings from patients with COVID-19 pneumonia in Babol North of Iran: a retrospective cohort study.

Background: In December 2019, China has experienced an outbreak of novel coronavirus disease 2019 (COVID-19). Coronavirus has now spread to all of the continents. We aimed to consider clinical characteristics, laboratory data of COVID-19 that provided more information for the research of this novel virus.

Influenza Vaccination and Guillain-Barré Syndrome: Reality or Fear.

Guillain-Barré syndrome (GBS) is an inflammatory disorder and an acute immune-mediated demyelinating neuropathy that causes reduced signal transmissions, progressive muscle weakness, and paralysis. The etiology of the syndrome still remains controversial and uncertain. GBS can be initiated and triggered by respiratory tract infections such as influenza, and intestinal infections such as .

Spontaneous relapse in patients with inactive chronic hepatitis B virus infection.

Background: Chronic hepatitis B virus infection (HBV) may reactivate during the course of the disease and is called spontaneous relapse. The purpose of this study was to evaluate the incidence of relapse of hepatitis in subjects with inactive HBV carriers.

Methods: This follow-up study was performed on 785 patients with inactive HBV carriers that were followed-up at six month intervals.

Zika virus: epidemiology, clinical aspects, diagnosis, and control of infection.

Zika virus (ZIKV) is an emerging pathogen of huge public health significance to human beings. Although majority of infections are benign with self-limiting symptoms, the recent outbreak has established an association with the increased incidence of some congenital anomalies such as microcephaly. In other words, due to the large extent of the virus and mosquito vectors, the infection has become a thoughtful health problem for human societies, though now, there are no antiviral therapies or vaccines against this virus.

Causal role of infectious agents in cancer: An overview.

Cancer is a complex group of diseases with multiple eventual causes. The underlying causes are not fully known. Thus, learning more about the known causes of cancer is an important issue.

Effects of Regular Treadmill Exercise on a DNA Oxidative-Damage Marker and Total Antioxidant Capacity in Rat Hippocampal Tissue.

Background And Purpose: Regular exercise can result in changes in the levels of oxidative stress in the hippocampus; however, little attention has been paid to physical-activity-induced neuronal protection to exposure to lead compounds. This study investigated the effects of regular treadmill exercise on a DNA oxidative-damage marker [8-hydroxy-2'-deoxyguanosine (8-OHdG)] and the total antioxidant capacity (TAC) of hippocampal tissue in lead-acetate exposed rats.

Methods: This study investigated the effects of 8 weeks of regular treadmill exercise on 8-OHdG and the TAC of hippocampal tissue in lead-acetate-exposed rats.

A study of the incidence of BCG vaccine complications in infants of Babol, Mazandaran (2011-2013).

Background: BCG vaccination which is administered to prevent tuberculosis is sometimes associated with serious complications. This study aimed to determine the incidence of complications of BCG vaccination in Babol.

Methods: All infants who received BCG vaccination between 2011-2013 in health centers of Babol entered the study.

Quantification and comparison of bone-specific alkaline phosphatase with two methods in normal and paget's specimens.

Background: Bone-specific alkaline phosphatase (BAP) is synthesized by the osteoblasts and is presumed to be involved in the calcification of bone matrix, though its precise role in the formation process is unknown. The aim of the present study was to measure the BAP activity in Paget's and normal specimens by two different techniques.

Methods: Total ALP (TAP) as well as BAP activity-measuring tests were repeatedly undertaken at different times during the day and different days on the serum samples (inter and intra assay).

Role of oxidative stress in pathogenesis of metabolic syndrome.

The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and cardiovascular diseases, has become one of the major public health challenges worldwide. The pathogenesis of the metabolic syndrome is multiple and still poorly understood. No single factor has yet been identified as an underlying causal factor.