Publications by authors named "Jijian Sun"
Article Synopsis
- The study evaluates how the herbal mixtures Hedyotis diffusa Willd (HDW) and Scutellaria barbata (SB) work therapeutically against clear cell renal cell carcinoma (ccRCC) by using advanced techniques like single-cell RNA sequencing (scRNA-seq) and network pharmacology.
- Researchers identified 29 crucial genes linked to the treatment effects of HDW-SB, confirming their potential in diagnosing and understanding immune responses in ccRCC through protein-protein interaction networks and molecular analysis.
- The findings highlight that specific active compounds (quercetin, luteolin, and baicalein) from HDW-SB interact with these hub genes, particularly affecting natural killer (NK) cells, and have
CircRNA SCARB1 Promotes Renal Cell Carcinoma Progression Via Mir- 510-5p/SDC3 Axis.
Curr Cancer Drug Targets
July 2021
Background: Emerging studies have indicated that circular RNAs (circRNAs) play important roles in the development of many tumors. CircRNA-scavenger receptor class B member 1 (Circ-SCARB1) was consistently reported as an elevated circRNA in RCC tissues. This study focused on examining the biological function and molecular mechanism of circSCARB1 in RCC progression.
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