Publications by authors named "Jijia Gou"
Hypertens Res
September 2024
Article Synopsis
- - The renin-angiotensin system (RAS) and the sympathetic nervous system (SNS) work together to regulate blood pressure, with prenatal exposure to lipopolysaccharide (LPS) driving increased RAS activity and sympathetic outflow in the paraventricular nucleus (PVN) of the brain.
- - This exposure leads to an imbalance of inhibitory and excitatory neurons, increased reactive oxygen species (ROS), and ultimately contributes to hypertension in offspring rats.
- - Melatonin treatment during pregnancy shows potential in reducing RAS activity and blood pressure, indicating it may help protect against hypertension caused by prenatal LPS exposure.
