Publications by authors named "Jiin Eom"
Article Synopsis
- Fibroblasts (hDFs) are important for skin healing but lose effectiveness due to cell aging, which has rarely been studied.
- Researchers are exploring the use of stem cell-derived nanovesicles (R-NVs) to enhance the functionality of aged fibroblasts while minimizing risks and improving yield.
- The study found that R-NVs made from red light-irradiated human adipose-derived stem cells rejuvenated old fibroblasts, enhancing their healing abilities and outperforming younger fibroblasts in skin wound healing.
Fibronectin-Enriched Interface Using a Spheroid-Converged Cell Sheet for Effective Wound Healing.
ACS Appl Mater Interfaces
March 2023
Cell sheets and spheroids are cell aggregates with excellent tissue-healing effects. However, their therapeutic outcomes are limited by low cell-loading efficacy and low extracellular matrix (ECM). Preconditioning cells with light illumination has been widely accepted to enhance reactive oxygen species (ROS)-mediated ECM expression and angiogenic factor secretion.
View Article and Find Full Text PDFVarious synthetic polymers based on poly(amino ester) (PAE) are suggested as candidates for gene and drug delivery owing to their pH-responsiveness, which contributes to efficient delivery performance. PAE-based pH-responsive polymers are more biodegradable and hydrophilic than other types of pH-responsive polymers. The functionality of PAE-based polymers can be reinforced by using different chemical modifications to improve the efficiency of gene and drug delivery.
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