Lactobacillus gasseri BNR17 and Limosilactobacillus fermentum ABF21069 Ameliorate High Sucrose-Induced Obesity and Fatty Liver via Exopolysaccharide Production and β-oxidation.

Obesity and metabolic dysfunction-associated fatty liver disease (MAFLD) are prevalent metabolic disorders with substantial global health implications that are often inadequately addressed by current treatments and may have side effects. Probiotics have emerged as promising therapeutic agents owing to their beneficial effects on gut health and metabolism. This study investigated the synergistic effects of a probiotic combination of BNR17 and ABF21069 on obesity and MAFLD in C57BL/6 mice fed a high-sucrose diet.

A hybrid PCA acceleration method for rapid real-time 2D MRI.

To develop a 2D MR acceleration method utilizing principal component analysis (PCA) in a hybrid fashion for rapid real-time applications.Retrospective testing was performed on 10 lung, 10 liver and 10 prostate 3T MRI data sets for image quality and target contourability. Sampling of k-space is performed by acquiring central (low-frequency) data in every frame while the high-frequency data is incoherently undersampled such that all of k-space is acquired in a pre-determined number of frames.

Seminal Vesicle Treatment for Localized Prostate Cancer Treated with External Beam Radiotherapy.

This study retrospectively reviewed data from men with localized prostate cancer treated with external beam radiotherapy (EBRT). We identified 359 men with localized prostate cancer treated with curative EBRT at the Cross Cancer Institute between 2010-2011. The volume of seminal vesicles (SVs) treated as well as dose values were extracted.

Inhibitory effect of fucoidan on TNF-α-induced inflammation in human retinal pigment epithelium cells.

() is a brown seaweed that contains a fucose-rich sulfated polysaccharide called fucoidan and is known to possess beneficial bioactivities, such as anti-inflammatory, antiviral, antioxidative, and antitumoral effects. This study aimed to determine the anti-inflammatory effects of AB_SH (hydrothermal extracts from ) and its bioactive compound (fucoidan) against tumor necrosis factor alpha (TNF-α)-induced inflammation in human retinal pigment epithelial (RPE) cells. AB_SH did not exhibit any cytotoxicity, and it decreased the mRNA expression of interleukin (IL)-6 and IL-8 and the production of the cytokines IL-6 and TNF-α.

National Survey of Sharps Injuries Incidence Amongst Healthcare Workers in the United States.

Purpose: Reporting sharps injuries is crucial for healthcare worker occupational safety. However, these incidents are often underreported, thus posing potentially dangerous working environments. Previous small and limited studies have quantified this underreporting in specific groups of healthcare workers.

Tumor Volume Predicts for Pathologic Complete Response in Rectal Cancer Patients Treated With Neoadjuvant Chemoradiation.

Objectives: Nonoperative management (NOM) of locally advanced rectal cancer is an emerging approach allowing patients to preserve their anal sphincter. Identifying clinical factors associated with pathologic complete response (pCR) is essential for physicians and patients considering NOM.

Materials And Methods: In total, 412 locally advanced rectal cancer patients were included in this retrospective analysis.

Host phylogeny, habitat, and diet are main drivers of the cephalopod and mollusk gut microbiome.

Background: Invertebrates are a very attractive subject for studying host-microbe interactions because of their simple gut microbial community and host diversity. Studying the composition of invertebrate gut microbiota and the determining factors is essential for understanding their symbiotic mechanism. Cephalopods are invertebrates that have similar biological properties to vertebrates such as closed circulation system, an advanced nervous system, and a well-differentiated digestive system.

Time domain principal component analysis for rapid, real-time 2D MRI reconstruction from undersampled data.

Purpose: A rapid real-time 2D accelerated method was developed for magnetic resonance imaging (MRI) using principal component analysis (PCA) in the temporal domain. This method employs a moving window of previous dynamic frames to reconstruct the current, real-time frame within this window. This technique could be particularly useful in real-time tracking applications such as in MR-guided radiotherapy, where low latency real-time reconstructions are essential.

More Is Not Better When It Comes to Treating Rectal Cancer With Multimodal Chemoradiation Beyond the Standard Radiation Dose of 5040 cGy.

Background: Radiation dose schedules for neoadjuvant chemoradiation for rectal cancers differ, with the most common dose schedule using 5040 cGy in 28 fractions.

Objectives: The aim of this retrospective study was to assess the benefit of higher radiation doses beyond 5040 cGy in the context of pathological response and follow-up events.

Setting: The database from a provincial tertiary cancer center in Canada was the source of information for this study.

sp. nov., isolated from the intestine of the dark diving beetle , and sp. nov., isolated from the intestine of the diving beetle .

A polyphasic taxonomic approach was used to characterize two novel bacterial strains, designated as HDW11 and HDW19, isolated from intestine samples of the dark diving beetle and the diving beetle , respectively. Both isolates were Gram-stain-positive, facultatively anaerobic and non-motile. Strain HDW11 grew optimally at 30 °C, pH 8 and in the presence of 1% (w/v) NaCl.

Leucobacter coleopterorum sp. nov., Leucobacter insecticola sp. nov., and Leucobacter viscericola sp. nov., isolated from the intestine of the diving beetles, Cybister brevis and Cybister lewisianus, and emended description of the genus Leucobacter.

Three novel bacterial strains, HDW9A, HDW9B, and HDW9C, isolated from the intestine of the diving beetles Cybister lewisianus and Cybister brevis, were characterized as three novel species using a polyphasic approach. The isolates were Gram-staining-positive, strictly aerobic, non-motile, and rod-shaped. They grew optimally at 30°C (pH 7) in the presence of 0.

sp. nov., isolated from the faeces of the oriental stork, .

A novel Gram-stain-positive, non-motile, non-spore-forming, coccobacillus-shaped, strictly aerobic bacterium, designated strain H23T48, was isolated from the faecal sample of an oriental stork collected from the Seoul Grand Park Zoo in Seoul, Republic of Korea. Optimal growth of strain H23T48 was observed at 30-37 °C, pH 8 and with 3 % (w/v) NaCl. 16S rRNA gene sequence-based phylogenetic analysis revealed that strain H23T48 was closely related to the genus , with 97.

Dosimetric Parameters Predicting Late Small Bowel Toxicity in Patients With Rectal Cancer Receiving Neoadjuvant Chemoradiation.

Purpose: The aim of this study was to identify dosimetric parameters that predict late small bowel (SB) toxicity after neoadjuvant long course chemoradiation (CRT) for rectal cancer.

Methods And Materials: Four hundred eighty-six consecutive patients with locally advanced rectal cancers (clinical T3/T4 or N1/N2) who received CRT followed by surgery and had dosimetric data available for analysis were included in this study. The dose-volume relationship between small bowel irradiation and late small bowel toxicity was evaluated and a mathematical model to predict for late SB toxicity was derived.

Two-Ply Carbon Nanotube Fiber-Typed Enzymatic Biofuel Cell Implanted in Mice.

Implantable devices have emerged as a promising industry. It is inevitable that these devices will require a power source to operate in vivo. Thus, to power implantable medical devices, biofuel cells (BFCs) that generate electricity using glucose without an external power supply have been considered.

Real-Time Lung Tumor Tracking Using a CUDA Enabled Nonrigid Registration Algorithm for MRI.

Objective: This study intends to develop an accurate, real-time tumor tracking algorithm for the automated radiation therapy for cancer treatment using Graphics Processing Unit (GPU) computing. Although a previous moving mesh based tumor tracking approach has been shown to be successful in delineating the tumor regions from a sequence of magnetic resonance image, the algorithm is computationally intensive and its computation time on standard Central Processing Unit (CPU) processors is too slow to be used clinically especially for automated radiation therapy system.

Method: A re-implementation of the algorithm on a low-cost parallel GPU-based computing platform is utilized to accelerate this computation at a speed that is amicable to clinical usages.

sp. nov., isolated from the faeces of an Oriental stork.

A novel, Gram-stain-positive, non-spore-forming, facultatively anaerobic bacterium, designated strain H21T32, was isolated from the faeces of an Oriental stork, . Cells formed cocci grouped in pairs, tetrads or conglomerates, and colonies on solid medium were pale yellow. Strain H21T32 belonged to the genus , family , order and class .

Single patient convolutional neural networks for real-time MR reconstruction: coherent low-resolution versus incoherent undersampling.

Accelerated MRI involves undersampling k-space, creating unwanted artifacts when reconstructing the data. While the strategy of incoherent k-space acquisition is proven for techniques such as compressed sensing, it may not be optimal for all techniques. This study compares the use of coherent low-resolution (coherent-LR) and incoherent undersampling phase-encoding for real-time 3D CNN image reconstruction.

sp. nov., isolated from the intestinal tract of a Korean indigenous freshwater fish, .

A novel Gram-negative, obligately aerobic, rod-shaped and non-motile bacterium, designated strain K13M18, was isolated from the intestinal tract of a Korean indigenous fish, oily bitterling (). Strain K13M18 formed creamy-pink colonies on a marine agar plate. Results of phylogenetic analysis based on the 16S rRNA gene sequence similarity indicated that strain K13M18 was most closely related to DRYC-M-16, sharing 97.

sp. nov., isolated from the gut of the Korean scallop, .

A novel Gram-stain-negative, aerobic, rod-shaped, reddish-orange-coloured, gliding bacterial strain, designated L12M1, was isolated from the gut of the Korean scallop, . Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain L12M1 formed a monophyletic clade with the strains in the genus and showed highest 16S rRNA gene sequence similarity to YS10 (98.66 %).

Single patient convolutional neural networks for real-time MR reconstruction: a proof of concept application in lung tumor segmentation for adaptive radiotherapy.

Investigate 3D (spatial and temporal) convolutional neural networks (CNNs) for real-time on-the-fly magnetic resonance imaging (MRI) reconstruction. In particular, we investigated the applicability of training CNNs on a patient-by-patient basis for the purpose of lung tumor segmentation. Data were acquired with our 3 T Philips Achieva system.

sp. nov., isolated from Korean shiner intestine.

A novel Gram-stain-negative, non-spore-forming, obligate aerobic, motile, rod-shaped, and flagellated bacterium, designated S11R28, was isolated from the intestinal tract of a Korean shiner, . Based on 16S rRNA gene sequences, strain S11R28 was identified as member of the genus in class , and was closely related to DSM 23061 (98.49 %).

sp. nov., a bacterium isolated from feces of oriental stork, .

A novel Gram-stain-negative, facultatively anaerobic, non-motile, non-violet-pigmented, rod-shaped bacterium, designated strain H11R3, was isolated from the feces of Oriental stork, , collected from Seoul Grand Park Zoo, Republic of Korea. Phylogenetic analysis of the 16S rRNA gene sequence revealed that H11R3 formed a monophyletic clade with DSM 3764, DSM 100243, and DSM 103822, with sequence similarities of 98.8, 98.