Publications by authors named "Jihyoun Kim"
Regulatory T (Treg) cells are essential for maintaining immune homeostasis by suppressing excessive immune responses. In the context of cancer, however, Tregs promote immune evasion and tumor progression, particularly through their unique adaptations within the tumor microenvironment (TME). Recent research has emphasized how metabolic characteristics shape Treg activation, migration, and immunosuppressive function, revealing the impact of metabolic pathways on Treg fitness in homeostasis and within the TME.
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- Rheumatoid arthritis (RA) is a long-term inflammatory disease affecting joints, but treatment with TNF-α inhibitors has improved management, despite potential adverse skin reactions.
- A cohort study explored genetic risk factors for skin reactions induced by TNF-α inhibitors in RA patients using machine learning to analyze genetic data and develop a risk-scoring system.
- Key findings revealed that specific genetic markers significantly increased the likelihood of skin adverse events, with varying risk scores indicating a high correlation between score and incidence rates of skin complications, paving the way for personalized treatment approaches.
We observe the hysteresis of a spontaneous symmetry breaking (SSB) transition in a parametrically modulated magneto-optical trap by sweeping the total number of atoms and study thermal hysteretic behavior in the system by measuring the scaling exponent of hysteresis. It is shown that the relaxation time of the order parameter in the SSB transition becomes larger near the critical number. The scaling exponent of the hysteresis area with number sweeping rate is found to be 0.
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