Publications by authors named "Jihye Lim"

Backgrounds/aims: Microwave ablation (MWA) is an emerging ablative therapy that surpasses previous methods by achieving higher temperatures and creating larger ablation zones within shorter periods. This study compared the therapeutic outcomes of MWA with those of liver resection in real-world clinical practice.

Methods: A total of 178 patients with 259 nodules who underwent MWA or liver resection between January 2015 and July 2023 were enrolled.

View Article and Find Full Text PDF

Epilepsy is a common neurological disorder in children, associated with significant morbidity and socioeconomic burden. The coronavirus disease 2019 (COVID-19) pandemic disrupted healthcare delivery, potentially exacerbating seizure control among pediatric epilepsy patients. This study aimed to evaluate the pandemic's impact on seizure characteristics and identify risk factors contributing to seizure exacerbation in children with epilepsy.

View Article and Find Full Text PDF

Background & Aims: Large-scale studies on the association between primary biliary cholangitis (PBC) and hepatocellular carcinoma (HCC) in Asians are scarce. This study aimed to evaluate the incidence of HCC and its risk factors in a nationwide cohort.

Methods: The data of 4,882 patients with PBC and 38,603 matched controls were extracted from the Korean National Health Insurance Service (2007-2020) and analyzed.

View Article and Find Full Text PDF

Background: Non-surgical method is a treatment option for mandibular condylar fracture; however, it is questionable whether bone fragments are adequately reduced and remodeled. The purpose of this study was to identify three-dimensional positional changes in the mandibular condyles in patients treated non-surgically, analyze factors influencing the extent of positional changes, and evaluate clinical prognosis.

Methods: This retrospective study included 31 patients with unilateral mandibular condylar fractures treated non-surgically at the Ajou University Dental Hospital between 2005 and 2023.

View Article and Find Full Text PDF

Introduction: Nationwide, population-based data on the risk of extrahepatic malignancy in patients with autoimmune hepatitis (AIH) in Asian countries are scarce. This study aimed to examine the risk of developing extrahepatic malignancies in a nationwide cohort of patients with AIH.

Methods: Using claims data from the Korean National Health Insurance Service database, patients diagnosed with AIH between 2007 and 2019 (n = 7,382) were matched in a 1:8 ratio with an age- and sex-matched control population (n = 58,320).

View Article and Find Full Text PDF

Background And Aims: This study aims to develop and validate a machine learning (ML) model predicting hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients after the first 5 years of entecavir (ETV) or tenofovir (TFV) therapy.

Methods: CHB patients treated with ETV/TFV for > 5 years and not diagnosed with HCC during the first 5 years of therapy were selected from two hospitals. We used 36 variables, including baseline characteristics (age, sex, cirrhosis, and type of antiviral agent) and laboratory values (at baseline, at 5 years, and changes between 5 years) for model development.

View Article and Find Full Text PDF

Characterized by UCP1 expression and abundant mitochondria, brown adipose tissue (BAT) plays a crucial role in energy balance by converting chemical energy into heat through the cost of ATP production. In this study, it was demonstrated that Trib3 is a critical determinant of BAT-mediated energy expenditure and whole-body energy homeostasis. Under 60% high-fat diet conditions, Trib3 expression in BAT was elevated.

View Article and Find Full Text PDF
Article Synopsis
  • - The study explored the relationship between steatotic liver disease (SLD) and various comorbidities, analyzing how the duration of these conditions affects SLD occurrence and mortality using data from the Korea National Health and Nutrition Examination Survey.
  • - Findings indicated that shorter durations of diabetes mellitus (DM) and dyslipidemia, and longer durations of hypertension (HTN) were significant factors for developing SLD, with particularly high risks associated with DM lasting less than a year.
  • - The research concluded that considering the duration of comorbidities is crucial for assessing SLD risk and prognosis, highlighting that longer durations of HTN and DM correlate with higher mortality risks.
View Article and Find Full Text PDF

Purpose: To investigate the epidemiological trends and socioeconomic disparities associated with ankylosing spondylitis (AS) in South Korea over a decade (2010-2021) using National Health Insurance Service (NHIS) claims data.

Materials And Methods: Employing data from the NHIS database, this study identified 31753 incident AS patients in 2010-2021. We calculated the annual age-standardized prevalence and incidence rates and analyzed crude incidence rates and diagnostic patterns across age groups.

View Article and Find Full Text PDF

Background/aims: This study aimed to evaluate the impact of steatotic liver disease severity on the cumulative incidence of lung cancer utilizing data from the Korea National Health Insurance Service (NHIS).

Methods: This study examined the risk of lung cancer in the general population in conjunction with the incidence of steatotic liver disease. The study population consisted of 3,261,438 individuals aged 20 years or older who underwent a general health examination in 2009.

View Article and Find Full Text PDF

Objectives: To analyze the characteristics of hospital injured patients and the factors that affect treatment results.

Methods: We used the data from the Korea National Hospital Discharge In-depth Injury Survey from 2019 to 2021 of the Korea Disease Control and Prevention Agency (KDCA), 18,037 people who experienced hospital injury accidents were analyzed. In a retrospective cross-sectional study, general characteristics and injury-related characteristics of patients with hospital-acquired injuries were collected.

View Article and Find Full Text PDF

Background: Previous studies have consistently reported a decrease in hospital admissions for respiratory diseases during the coronavirus disease 2019 (COVID-19) pandemic. However, the impact of the pandemic on idiopathic pulmonary fibrosis (IPF) admissions remains unknown.

Methods: This study used data from the Korean National Health Insurance Service database.

View Article and Find Full Text PDF

Background: Breathlessness shares aging mechanisms with frailty and sarcopenia.

Research Question: Are frailty and sarcopenia associated with breathlessness itself?

Study Design And Methods: We analyzed data from a population-based, prospective cohort study of 780 community-dwelling older adults. Breathlessness was defined using the modified Medical Research Council dyspnea scale (≥ 2 points) and the COPD Assessment Test (≥ 10 points).

View Article and Find Full Text PDF
Article Synopsis
  • Obstructive sleep apnea (OSA) significantly affects health-related quality of life (QoL), particularly among different demographics in the Korean population, with those at high risk reporting lower QoL scores than those at low risk.
  • * A study utilizing data from the Korean National Health and Nutrition Examination Survey found that out of nearly 9,000 adults, 24.2% were classified as high risk for OSA, with notable differences in QoL observed mainly in elderly females.
  • * Results indicate that while high risk OSA negatively impacts QoL, comorbidities have an even greater effect, emphasizing the need to consider these factors when evaluating QoL in patients.
View Article and Find Full Text PDF
Article Synopsis
  • A study explored the unclear relationship between diabetes and clinical outcomes in patients with alcoholic liver cirrhosis by analyzing data from 965 patients admitted due to acute decompensation from 2015 to 2019.* -
  • Results showed that 23.6% of participants had diabetes, which correlated with increased risks for complications like hepatic encephalopathy and upper gastrointestinal bleeding. Notably, the incidence of death or liver transplantation was higher among diabetic patients.* -
  • The findings concluded that diabetes significantly increases the risk of death or liver transplantation in these patients, leading to poorer health outcomes over time.*
View Article and Find Full Text PDF

Zero-excess Li-metal batteries (ZE-LMBs) have emerged as the ultimate battery platform, offering an exceptionally high energy density. However, the absence of Li-hosting materials results in uncontrolled dendritic Li deposition on the Cu current collector, leading to chronic loss of Li inventory and severe electrolyte decomposition, limiting its full utilization upon cycling. This study presents the application of ultrathin (≈50 nm) coatings comprising six metallic layers (Cu, Ag, Au, Pt, W, and Fe) on Cu substrates in order to provide insights into the design of Li-depositing current collectors for stable ZE-LMB operation.

View Article and Find Full Text PDF

Large-scale studies on the risk of fragility fractures in patients with primary biliary cholangitis (PBC) are limited due to low incidence. We aimed to investigate whether PBC is associated with fragility fractures using real-world nationwide data. The Korean National Health Insurance Service claims data from 2007 to 2020 were analyzed in this population-based cohort study.

View Article and Find Full Text PDF
Article Synopsis
  • * The findings showed that participants at high risk for OSA (identified through the STOP-Bang questionnaire) had significantly higher uric acid levels (5.5 mg/dL vs. 4.8 mg/dL) and a positive correlation between uric acid levels and OSA risk scores.
  • * The analysis concluded that hyperuricemia is an independent risk factor for OSA, suggesting a need for further research into the long-term effects of high uric acid levels
View Article and Find Full Text PDF

Background And Aim: The Model for End-Stage Liver Disease (MELD) is a reliable prognostic tool for short-term outcome prediction in patients with end-stage liver disease. MELD 3.0 was introduced to enhance the predictive accuracy.

View Article and Find Full Text PDF

Smart cities have emerged as a promising solution to the problems associated with urbanization. However, research that holistically considers diverse stakeholders in smart cities is scarce. This study utilizes data from four types of collaborators (academia, public sector, industry, and civil society actors) to identify key topics and suggest research areas for developing smart cities.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focuses on three autoimmune liver diseases: Autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC), which are rare and often difficult to diagnose and treat.
  • - Data from the National Health Insurance Service in Korea (2005-2019) revealed a predominance of females in AIH (83.9%) and PBC (83.3%), while PSC showed no sex dominance, with respective mean ages of diagnosis around 56-58 years.
  • - The prevalence of these diseases is rising, with 2019 statistics showing AIH at 18.4 per 100,000, PBC at 11.8, and PSC
View Article and Find Full Text PDF

Late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMRI) reflects the burden of myocardial damage in carbon monoxide (CO) poisoning. This study aimed to identify the clinical and echocardiographic parameters that can predict myocardial LGE on CMRI in CO poisoning. This prospective observational study included patients who presented with acute CO poisoning and elevated troponin I and underwent echocardiography and CMRI to identify myocardial damage at a tertiary university hospital between August 2017 and May 2019 and August 2020 and July 2022.

View Article and Find Full Text PDF

Background: Epinephrine is administered to increase coronary perfusion pressure during advanced life support and promote short-term survival. Recent cardiopulmonary resuscitation (CPR) guidelines recommend an epinephrine dosing interval of 3 to 5 minutes during resuscitation; however, scientific evidence supporting this recommendation is lacking. Therefore, we aimed to investigate the hemodynamic effects of repeated epinephrine doses during CPR by monitoring augmented blood pressure after its administration in a swine model of cardiac arrest.

View Article and Find Full Text PDF

Purpose: Accurate estimation of survival is of utmost importance in patients with hepatocellular carcinoma (HCC) and extrahepatic metastasis. This study aimed to develop a survival prediction model using real-world data.

Patients And Methods: A total of 993 patients with treatment-naïve HCC and extrahepatic metastasis were included from 13 Korean hospitals between 2013 and 2018.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session5har526fo32hka63e5pgkr2hq56g3e2q): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once