Study on migration instability characteristics and mine pressure control of roof overburden rock in thin coal seams mining.

In the Guxu mining area, the mining of thin coal seams is complicated by the unknown migration structure of the roof overburden and severe mine pressure. Based on this, taking the 1599 working face as the research background, and using a method that combines theory with simulation, starting from the structural fracture of roof overburden rock in thin coal seams, the roof failure characteristics during the mining process are studied, and the roof caving shape and stress distribution characteristics under the influence of mining speed are studied is explored. The research results show that a cantilever beam with a short length forms in the overburden rock of the soft bedrock roof during thin coal seams mining.

Age-related changes of dopamine D1 and D2 receptors expression in parvalbumin-positive cells of the orbitofrontal and prelimbic cortices of mice.

Dopamine (DA) plays a pivotal role in reward processing, cognitive functions, and emotional regulation. The prefrontal cortex (PFC) is a critical brain region for these processes. Parvalbumin-positive (PV+) neurons are one of the major classes of inhibitory GABAergic neurons in the cortex, they modulate the activity of neighboring neurons, influencing various brain functions.

Development and validation of mathematical nomogram for predicting the risk of poor sleep quality among medical students.

Background: Despite the increasing prevalence of poor sleep quality among medical students, only few studies have identified the factors associated with it sing methods from epidemiological surveys. Predicting poor sleep quality is critical for ensuring medical Students' good physical and mental health. The aim of this study was to develop a comprehensive visual predictive nomogram for predicting the risk of poor sleep quality in medical students.

Metabolomic Identification of Serum Exosome-Derived Biomarkers for Bipolar Disorder.

Background: Exosomes are extracellular vesicles that play important roles in various physiological and pathological functions. Previous studies have demonstrated that exosome-derived contents are promising biomarkers to inform the pathogenesis and diagnosis of major depressive disorder and schizophrenia.

Methods: We used ultraperformance liquid chromatography-tandem mass spectrometry to analyze the differentially expressed metabolites in serum exosomes of patients with bipolar disorder (BD) and evaluated the potential of exosomal metabolites as biomarkers for BD.

[Multiscale influences of urbanized landscape metrics on the diversity of indigenous plant species: A case study in Shunyi District of Beijing, China.].

The effects of landscape pattern on plant diversity have been widely reported in literature, with that of urban landscape remaining largely unknown. To explore the impacts of urbanization landscape pattern on plant diversity and its scale effect, 105 plots were investigated in Shunyi District, Beijing. The α and β diversity of each plot were calculated, and 43 urban landscape indices of 10 scales in the range of 100-1000 m were analyzed with 100 m as the step.