Publications by authors named "Jignesh Magudia"
Article Synopsis
- The integrin-adhesome network, comprising over 150 proteins, plays a crucial role in muscle structure and function, particularly at cell interfaces.
- Researchers knocked down 113 genes in C. elegans related to the mammalian adhesome and found that over 90% of these proteins are essential for proper muscle mitochondrial structure and function.
- The study reveals that disruptions in the entire adhesome lead to muscle dystrophy and decreased energy production, underscoring its importance in muscle health.
