The influence of drug prices, new availability of inexpensive generic imatinib, new approvals, and post-marketing research on the treatment of chronic myeloid leukaemia in the USA.

Several research and market developments in the past 5 years could influence front-line and subsequent-line strategies in chronic myeloid leukaemia. These developments include the increased availability of effective and safe generic imatinib at affordable prices, studies showing that doses of tyrosine kinase inhibitors (TKIs) lower than the approved dose are effective and less toxic, studies showing that dose-adjusted ponatinib therapy at a reduced dose is effective and substantially safer than approved doses, and the approval of asciminib as third-line therapy in 2021. With the availability of an affordable generic imatinib, all patients with chronic myeloid leukaemia globally should be able to access a lifetime supply.

Effectiveness of oral health education on knowledge, attitude, practices and oral hygiene status among 12-15-year-old schoolchildren of fishermen of Kutch district, Gujarat, India.

Background: To assess the effectiveness of oral health education on oral health knowledge, attitude, practices and oral hygiene status among 12-15-year-old school children of fishermen of Kutch district, Gujarat, India.

Materials And Methods: A before-and-after experimental study was conducted among all (n = 205) the 12-15-year-old children from two schools of Bhadreshwar village of Mundra taluka of Kutch district, Gujarat, India from January 2013 to December 2013. At baseline, children were assessed for oral health knowledge, attitude and practices using a self-administered structured questionnaire and oral hygiene was assessed using Oral Hygiene Index-Simplified (OHI-S).

Assessment of intelligence quotient among schoolchildren of fishermen community of Kutch, Gujarat, India.

Background And Aim: The aim of the study was to assess the intelligence quotient of fishermen school children of Kutch, Gujarat, India.

Materials And Methods: A descriptive cross-sectional study was conducted among 8 to 10 years old school children living in Kutch District, Gujarat, India, from January to February 2013. Seguin Form Board Test was used to assess the intelligence quotient (IQ) level of children.