Hypoxia impairs male reproductive functions via inducing rat Leydig cell ferroptosis under simulated environment at altitude of 5000 m.

Aims: Many studies demonstrated reproductive damage in men residing in plains who are exposed to hypoxia at high altitudes. However, little is known about mechanisms between male reproductive impairment and hypobaric hypoxia. Hypoxia is one of the reasons for the imbalance of cellular redox system.

Vagal predominance correlates with mood state changes of winter-over expeditioners during prolonged Antarctic residence.

Objective: Winter-over expeditioners in Antarctica are challenged by various environmental and psycho-social stress factors, which may induce psychophysiological changes. The autonomic nervous system (ANS) plays a crucial role in the adaptation process under stress. However, the relationship between ANS activity and the mood states of expeditioners remains largely unexplored.

Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia.

Cardiovascular function and adipose metabolism were markedly influenced under high altitudes. However, the interplay between adipokines and heart under hypoxia remains to be elucidated. We aim to explore alterations of adipokines and underlying mechanisms in regulating cardiac function under high altitudes.

Neural Network Compression Based on Tensor Ring Decomposition.

Deep neural networks (DNNs) have made great breakthroughs and seen applications in many domains. However, the incomparable accuracy of DNNs is achieved with the cost of considerable memory consumption and high computational complexity, which restricts their deployment on conventional desktops and portable devices. To address this issue, low-rank factorization, which decomposes the neural network parameters into smaller sized matrices or tensors, has emerged as a promising technique for network compression.

Hypoxia promotes white adipose tissues browning in rats under simulated environment at altitude of 5000 m.

People living in plains tend to decrease in body weight or body fat percentage after entering the plateau. Previous studies have found that plateau animals can burn fat and release calories through white adipose tissues (WATs) browning. However, these studies have focused on the effect of cold stimulation that induced WATs browning while there's hardly study on the effect of hypoxia.