Palladium-Catalyzed Annulative π-Extension of Bay-Iodinated Triphenylenes to Access Polycyclic Aromatic Compounds.

A palladium-catalyzed annulative π-extension reaction of bay-iodinated triphenylenes with aryl iodides/-chloroaromatic carboxylic acids was developed. This approach enabled the synthesis of diverse polycyclic aromatic compounds, including dibenzo[,]tetracenes, azadibenzo[,]tetracenes, and tribenzo[,,]coronenes. Initial studies indicate that the resulting product, 2,3,8,9,14,15-hexakis(decyloxy)tribenzo[,,]coronene, exhibits good liquid-crystalline properties.

Palladium-catalyzed annulative π-extension of -halobiphenyls with -chloropyridinecarboxylic acids to access azatriphenylenes.

A palladium-catalyzed bay-region annulative π-extension reaction of -halobiphenyls with -chloropyridinecarboxylic acids was developed. The reaction was carried out with a 1 : 1 ratio of substrates. A variety of azatriphenylene derivatives could be synthesized by this approach.

Generation of a human iPSC line ZZUNEUi014-A from a patient with antithrombin deficiency caused by mutation in SERPINC1 gene.

Inherited antithrombin (AT) deficiency is an autosomal dominant disorder associated with SERPINC1 mutations. In this study, we generated a human induced pluripotent stem cell (iPSC) line ZZUNEUi014-A from peripheral blood mononuclear cells of a female AT deficiency patient with the p. W27X (c.

Sonographic Features and Diagnosis of Peripheral Schwannomas.

Background: To determine the sonographic features of peripheral schwannomas.

Methods: This retrospective study included 54 cases of schwannoma in 51 patients. Ultrasonography (US) and MRI were performed in all patients.

Protective effects of epigallocatechin-3 gallate on atrial electrical and structural remodeling in a rabbit rapid atrial pacing model.

Epigallocatechin-3 gallate (EGCG) is the major catechin in green tea. The aim of this study is to investigate the effects of EGCG on atrial electrical and structural remodeling in a rabbit rapid atrial pacing (RAP) model. New Zealand white rabbits were subjected to RAP with or without EGCG treatment.

Transition of 1628C > T in mitochondrial tRNAVal gene should not be regarded as a mutation associated with hypertrophic cardiomyopathy.

Diagnosis of hypertrophic cardiomyopathy (HCM) involved the screening for the candidate pathogenic mitochondrial DNA (mtDNA) mutations. However, a poor genotype to phenotype correction is common. Neutral polymorphisms in mt-tRNA gene are recognized as a potential cause for HCM.