Effect of Aerobic Exercise Training on Circulating Fibroblast Growth Factor-21 Response to Glucose Challenge in Overweight and Obese Men: A Pilot Study.

Background And Study Purpose: Fibroblast growth factor-21 (FGF21) is a liver-derived hormone that lowers blood glucose. Although aerobic exercise training also lowers blood glucose, its effect on circulating FGF21levels remains obscure. This study aimed to examine the effect of aerobic exercise training on serum FGF21 levels in overweight and obese men.