Identification of and sp. in Malayan pangolins-a potential threat to public health?

Unlabelled: The discovery of severe acute respiratory syndrome-coronavirus-2-like and Middle East respiratory syndrome-coronavirus-like viruses in Malayan pangolins has raised concerns about their potential role in the spread of zoonotic diseases. Herein, we describe the isolation and whole-genome sequencing of potentially zoonotic two bacterial pathogens from diseased Malaysian pangolins ()- and sp. The newly identified species were designated as P69 and sp.

Clonal spread of blaNDM-1-carrying Salmonella enterica serovar Typhimurium clone ST34 and wide spread of IncHI2/ST3-blaNDM-5 plasmid in China.

Objectives: To characterize blaNDM-carrying Salmonella recovered from a pig slaughterhouse.

Methods: In this study, 46 environment samples were collected from a slaughterhouse in China, and screened for carbapenem-resistant Enterobacterales. WGS, antimicrobial susceptibility testing and conjugation experiments were carried out to identify the isolates' resistance phenotypes and genetic characteristics.

Multiple Copies of Mobile Tigecycline Resistance Efflux Pump Gene Cluster Identified in Chromosome of spp.

The appearance and prevalence of novel plasmid-encoded tigecycline resistance efflux pump gene clusters and in have raised a threat to public health. Here, another tigecycline resistance gene cluster, , was identified in two isolates recovered from fish meat and vegetables. Cloning confirmed the expression of mediated the resistance to tigecycline and decreased susceptibility to tetracyclines and cephalosporins in both Escherichia coli and .