Background: Metabolic syndrome (MS) refers to a cluster of metabolic disorders characterized by systemic chronic inflammation. Er Miao San (EMS) is a classic traditional Chinese medicine compound containing Phellodendron amurense and Atractylodis rhizome at a ratio of 1:1, proven to be effective against inflammatory diseases in clinical practice. Nevertheless, the precise functions of EMS in treating MS and its underlying mechanism have yet to be elucidated.
View Article and Find Full Text PDFBiochim Biophys Acta Mol Cell Res
December 2024
The role of micropeptide in cardiomyocyte proliferation remains unknown. We found that MPM (micropeptide in mitochondria) was highly expressed in cardiomyocytes. Compared to MPM mice, MPM knockout (MPM) mice exhibited reduction in left ventricular (LV) mass, myocardial thickness and LV fractional shortening.
View Article and Find Full Text PDFThis study aimed to evaluate the effects of Chinese herbal mixtures (CHMs) on productive performance, egg quality, immune status, anti-apoptosis ability, caecal microbiota, and offspring meconial microbiota in hens. A total of 168 thirty-week-old Wenchang breeder hens were randomly divided into two groups, with each group comprising six replicate pens of fourteen hens. The groups were fed a basal diet (CON group) and a basal diet with 1,000 mg/kg CHMs (CHMs group) for 10 weeks.
View Article and Find Full Text PDFThe aim of this study was to investigate the effects of adding perilla seed meal (PSM) to the diet on reproductive performance, egg quality, yolk fatty acids, antioxidant capacity and liver lipid metabolism in breeding hens. A total of 192 31-week-old yellow-feathered hens were randomly divided into 4 treatments with 6 replicates of 8 birds for 8 weeks. The chickens were fed a typical corn-soybean meal diet containing 0% (control), 0.
View Article and Find Full Text PDFChinese herbs have been used as feed additives and are commonly utilized in domestic intensive livestock farming. However, their impact on the production performance and intestinal health of broiler breeders has yet to be thoroughly explored. This study aimed to evaluate the effects of a Chinese herbal mixture (CHM) on the production performance of broiler breeders in terms of reproductive hormones, antioxidant capacity, immunity, and intestinal health of broiler breeders.
View Article and Find Full Text PDFPhytosterols (PS) have been shown to regulate cholesterol metabolism and alleviate hyperlipidemia (HLP), but the mechanism is still unclear. In this study, we investigated the mechanism by which PS regulates cholesterol metabolism in high-fat diet (HFD) mice. The results showed that PS treatment reduced the accumulation of total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C) in the serum of HFD mice, while increasing the serum levels of high-density lipoprotein cholesterol (HDL-C).
View Article and Find Full Text PDFThe current study focused on the effects of Shenling Baizhu San (SLBZS) fermented by (. ) on gut microbiota, antioxidant capacity, and intestinal barrier function of yellow-plumed broilers. Our results showed that the content of ginsenoside Rb1 was the highest when SLBZS were inoculated with 3% .
View Article and Find Full Text PDFShenling Baizhu San has beneficial effects on the metabolism of the gut microbiota, however, the mechanisms underlying microbiota metabolites mediated anti-inflammation signaling are not well understood. Previously, we have demonstrated that supplementation with Shenling Baizhu San alleviated antibiotic-associated diarrhea (AAD). The current study intends to investigate the dynamic modulation of Shenling Baizhu San polysaccharides (SP) on colitis from the gut microbiota metabolites perspective.
View Article and Find Full Text PDFAtopic dermatitis (AD) is a common chronic allergic skin disease characterized clinically by severe skin lesions and pruritus. L. (PO) is a resourceful plant with homologous properties in medicine and food.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
September 2019
In this assay, the triple-wavelength overlapping resonance Rayleigh scattering (TWO-RRS) method and the fluorescence quenching method for the quantitative detection of chitooligosaccharides (COS) were developed. In the weakly Britton-Robinson buffer solution, COS interacted with Trisodium-8-hydroxypyrene-1,3,6-trisulfonate (HPTS) to form an ion-association complex of HPTS-COS, which increased the RRS intensities at 321 nm, 430 nm and 511 nm and decreased the fluorescence intensities of the system at 512 nm. And the changes in the intensities of both methods were related to the changes in the concentration of COS.
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