Publications by authors named "Jieun Bang"
Article Synopsis
- This study introduces a nanohybrid designed to enhance both photothermal and photodynamic effects for treating cancer, combining various polymers and gold nanoparticles.
- The unique assembly method produces uniform nanoparticles quickly and effectively, showing potent results when activated by a single near-infrared wavelength.
- The nanohybrid not only inhibits tumor growth and boosts immune responses but also shows improved efficacy when paired with immune checkpoint inhibitors, making it a promising option for combined cancer therapies.
Organic charge-transfer complex (CTC) formation has emerged as an effective molecular engineering strategy for achieving the desired optical properties via intermolecular interactions. By synthesizing organic CTCs with carbazole-based electron donors and a 7,7,8,8-tetracyanoquinodimethane acceptor and adopting a molecular linker located remotely from the charge-transfer interface within the donors, we were able to modulate near-infrared absorptive and short-wavelength infrared emissive properties. Structural characterizations performed by using single-crystal X-ray diffraction confirmed that the unique molecular arrangements induced by the steric hindrance from the remotely located linker significantly influence the electronic interactions between the donor and acceptor molecules, resulting in different photophysical properties.
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- Researchers developed a crystalline supramolecular photocatalyst (CuPDI-Hm) by assembling a compound called perylene diimide with imidazole groups and copper, resulting in a nanorod shape.
- This new photocatalyst achieved a high oxygen evolution rate of 25,900 μmol g h without needing extra co-catalysts, demonstrating its efficiency.
- The coordination between copper and imidazole helps structure the molecules, creating an electric field that prevents the loss of photo-induced charges, enhancing overall photocatalytic performance compared to versions without copper.
Article Synopsis
- * Recent research has focused on the EGFR/PI3K/AKT/mTOR signaling pathway, which is crucial for the progression of HCC, highlighting its significance in hepatocarcinogenesis.
- * Targeting the components of this signaling pathway with small molecule inhibitors shows promise as a potential treatment strategy for HCC, as demonstrated by preclinical studies.
Effect of orally administered Lactobacillus brevis HY7401 in a food allergy mouse model.
J Microbiol Biotechnol
November 2013
Article Synopsis
- Oral Lactobacillus species were found to effectively modulate the immune response in mice sensitized to ovalbumin (OVA).
- The study specifically tested Lactobacillus brevis HY7401 in genetically modified mice and observed it promoted Th1 cytokines while inhibiting Th2 cytokines.
- The administration of this probiotic reduced all tested types of OVA-specific antibodies and decreased the severity of systemic anaphylaxis, suggesting its potential to aid in anti-allergic treatments.
Article Synopsis
- A study was conducted to evaluate the impact of different Lactobacillus probiotic strains on allergic responses in mice that were sensitized with ovalbumin (OVA).
- Mice received probiotics every two days for three weeks after being sensitized, and results showed that the Lactobacillus brevis HY7401 (L3) group had a significant decrease in total IgE levels, indicating a reduction in allergic responses.
- L3 also promoted an increase in beneficial Th1 cytokines while decreasing harmful Th2 cytokines, which contributed to its antiallergic effects, unlike the other strains that either maintained or worsened allergic symptoms.
Article Synopsis
- The cerebellum plays a key role in various complex functions and is impacted by prion diseases, which lead to problems like ataxia and cognitive decline.
- Researchers developed an immortal mouse cerebellar cell line (CRBL) to study the effects of prions, noting its rapid growth and ability to express both neuronal and glial markers.
- The study reveals that CRBL cells show selective susceptibility to prions, confirming that specific host-prion interactions are crucial, and suggests future research on the molecular mechanisms behind prion diseases.