Establishment and validation of a prognostic nomogram for severe fever with thrombocytopenia syndrome: A retrospective observational study.

Background: Several scoring systems have been proposed to predict the risk of death due to severe fever with thrombocytopenia syndrome (STFS), but they have limitations. We developed a new prognostic nomogram for STFS-related death and compared its performance with previous scoring systems and the Acute Physiology and Chronic Health Evaluation score (APACHE II Score).

Methods: A total of 292 STFS patients were retrospectively enrolled between January 2016 and March 2023.

Phylogenetic incongruence in an Asiatic species complex of the genus Caryodaphnopsis (Lauraceae).

Background: Caryodaphnopsis, a group of tropical trees (ca. 20 spp.) in the family Lauraceae, has an amphi-Pacific disjunct distribution: ten species are distributed in Southeast Asia, while eight species are restricted to tropical rainforests in South America.

Comparative analyses of eight complete plastid genomes of two hemiparasitic vines in the family Lauraceae.

is the sole genus of hemiparasitic vines (ca. 20 spp.) belonging to the Cassytheae tribe of the Lauraceae family.

Promotes the Progression of Colorectal Cancer Through Cdk5-Activated Wnt/β-Catenin Signaling.

Background/aims: Growing evidence supports the direct link of with colorectal cancer (CRC). However, to date, the underlying mechanism of action remains poorly understood. In this study, we examined the effects of on the progression of CRC and investigated whether cyclin-dependent kinase 5 (Cdk5) is involved in the effect through activating the Wnt/β-catenin signaling pathway.

Targeting STAT3 inhibition to reverse cisplatin resistance.

Cisplatin is one of the most frequently used chemotherapeutic agents for treatment of a wide range of cancer types. Nevertheless, the intrinsic or acquired resistance to cisplatin remains a major obstacle for cancer therapy. There are a number of factors contributing to the onset of this phenotype resistance.