Altered default-mode and frontal-parietal network pattern underlie adaptiveness of emotion regulation flexibility following task-switch training.

Emotion regulation flexibility (ERF) refers to one's ability to respond flexibly in complex environments. Adaptiveness of ERF has been associated with cognitive flexibility, which can be improved by task-switching training. However, the impact of task-switching training on ERF and its underlying neural mechanisms remain unclear.

Neurophysiological mechanisms underlying the influence of motivational intensity on emotion regulation choice.

Motivation is considered a crucial factor in determining emotion regulation choice (ER choice). Our previous study revealed that increased motivation led to a preference for distraction over reappraisal due to the narrowed attention, yet neural underpinnings supporting this phenomenon remain unclear. In this study, we used event-related potentials (ERPs) to investigate whether motivation influences ER choice by early attention processing (P2) or late resource engagement (LPP).

The neurophysiological effects of detached and positive reappraisal during the regulation of self-conscious emotions.

Background: While cognitive reappraisal represents a promising emotion regulation strategy in regulating basic emotions, little experimental research has investigated its efficacy in reducing self-conscious emotions such as shame and guilt.

Objective: The present study aimed to investigate the effectiveness of detached reappraisal and positive reappraisal in regulating feelings of shame and guilt, and also compared the effectiveness of these two strategies using behavioral and event-related potentials.

Method: Thirty-nine participants grouped either in positive reappraisal or detached reappraisal condition were informed to advise the decider to perform a dot-estimation task.

Situation covariation and goal adaptiveness? The promoting effect of cognitive flexibility on emotion regulation in depression.

Cognitive inflexibility as a generalized characteristic of depression has been closely implicated in maladaptive coping with changing situations and goals in daily life. The association between cognitive flexibility and depression can be elucidated by situation covariation and goal adaptiveness of emotion regulation flexibility (ERF), which facilitates adaptive responses to changing environments. However, little is known about the contribution of cognitive flexibility to emotion regulation in depression under changing situations and goals.

The critical mediating roles of the middle temporal gyrus and ventrolateral prefrontal cortex in the dynamic processing of interpersonal emotion regulation.

Interpersonal emotion regulation (IER) is a crucial ability for effectively recovering from negative emotions through social interaction. It has been emphasized that the empathy network, cognitive control network, and affective generation network sustain the deployment of IER. However, the temporal dynamics of functional connectivity among these networks of IER remains unclear.

The use of multilevel emotion regulation strategies in the context of critical public events: the more the better?

Critical public events, like COVID-19, significantly impact individuals' emotional and mental health. People tend to use multi-level emotion regulation strategies (intrapersonal, interpersonal and hyper-personal) to cope with these events, resulting in various strategy profiles. However, few studies have examined ER strategies from a multilevel perspective.

Hepatic infarction occurred after I particle stent treatment for hepatocellular carcinoma with portal vein tumor thrombus: A case report.

Background: Hepatic infarction is a rare liver condition. The purpose of this study is to report a case of hepatic infarction caused by thrombus formation following portal vein stent implantation in a patient with hepatocellular carcinoma and portal vein tumor thrombus, and to explore the underlying causes.

Case Report: The patient in this study was a 52-year-old male admitted with diffuse hepatocellular carcinoma involving the right lobe and portal vein tumor thrombus.

The association between social media use and well-being during quarantine period: testing a moderated mediation model.

Objectives: Social media use (SMU) increased dramatically during COVID-19 due to policies such as long-term quarantine. Given that SMU has complex effects on individuals' well-being, this study aimed to explore the relationship between SMU and subjective well-being and the influencing factors in the context of the pandemic in China.

Methods: A total of 895 adults (413 males) in different risk areas across China participated in this study.

Boosting interpersonal emotion regulation through facial imitation: functional neuroimaging foundations.

Empathic function, which is primarily manifested by facial imitation, is believed to play a pivotal role in interpersonal emotion regulation for mood reinstatement. To explore this association and its neural substrates, we performed a questionnaire survey (study l) to identify the relationship between empathy and interpersonal emotion regulation; and a task-mode fMRI study (study 2) to explore how facial imitation, as a fundamental component of empathic processes, promotes the interpersonal emotion regulation effect. Study 1 showed that affective empathy was positively correlated with interpersonal emotion regulation.

Unconscious and conscious acceptance downregulate aggressive behavior: Mediating role of anger regulation.

Social exclusion can induce negative emotions and aggression. While previous studies have investigated the effect of trait acceptance on emotional experience and aggression during social exclusion, it is still unclear how different forms of acceptance strategy can downregulate negative emotions and whether this potential reduction of negative emotions should mediate the effect of acceptance on aggression. To address these questions, 100 participants were recruited and randomly divided into three groups: control group (CG, N = 33), conscious acceptance group (CAG, N = 33) and unconscious acceptance group (UAG, N = 34).

Impact of cytoreduction and remission status on hematopoietic cell transplantation outcomes in pediatric myelodysplastic syndrome and related disorders.

Background: The role of cytoreduction prior to hematopoietic cell transplant (HCT) for patients with pediatric myelodysplastic syndrome (MDS) and related disorders remains unclear.

Procedure: We performed a single-center retrospective analysis of pre-transplant disease management and subsequent HCT outcome for pediatric patients with MDS and related disorders who underwent HCT between 2010 and 2020.

Results: Total 62 patients (median age 11 years) with idiopathic MDS (n = 16), MDS secondary to an underlying germline condition (n = 11), secondary acute myeloid leukemia (n = 9), myeloproliferative neoplasms (n = 8), and treatment-related myeloid neoplasms (n = 18) received an allogeneic HCT.

Awe weakens the AIDS-related stigma: The mediation effects of connectedness and empathy.

Stigma toward people with HIV or AIDS produces significant harms to their life and also hinders the prevention of AIDS. In the present study, we tested whether awe can weaken AIDS-related stigma and the mediating role of connectedness and empathy between them through a cross-sectional study (Study 1, = 372) and two experimental studies (Study 2a and 2b, = 110 and = 180, respectively). Results showed that awe reduced AIDS-related stigma (Study 2a and 2b), the serial mediation of connectedness and empathy (Study 1 and 2b).

Trait Acceptance Buffers Aggressive Tendency by the Regulation of Anger during Social Exclusion.

Social exclusion has led to increased negative emotions and aggressive behaviors, two outcomes that are correlated with each other. Thus, the down-regulation of negative emotions appears to play a crucial role in reducing the tendency for aggressive behavior. However, this assumption has not yet been tested.

Shared surname enhances our preference to famous people: multimodal EEG evidence.

Multimodal Electroencephalography techniques were used to determine whether the name of famous people undergoes self-relevant processing due to a shared surname with participants. During a three-stimulus oddball task, brain activity was recorded when participants suddenly saw their own names (self-name [SN]), a famous name with the same surname (FNS), or a famous name with a different surname (FND). While familiarity ratings were kept similar across the three kinds of name, behavioral analysis showed a higher rating on self-relevance for SN than for FNS, which, in turn, received a higher rating than FND.

Temporal dynamic patterns of the ventromedial prefrontal cortex underlie the association between rumination and depression.

As a major contributor to the development of depression, rumination has proven linked with aberrant default-mode network (DMN) activity. However, it remains unclear how the spontaneous spatial and temporal activity of DMN underlie the association between rumination and depression. To illustrate this issue, behavioral measures and resting-state functional magnetic resonance images were connected in 2 independent samples (NSample1 = 100, NSample2 = 95).

Increased motivational intensity leads to preference for distraction over reappraisal during emotion regulation: Mediated by attentional breadth.

Motivation is considered important in the study of emotion regulation. However, it remains unknown whether and how varied motivation may influence people's emotion regulation choice. To address this question, 51 participants first performed a global-local task that measures attentional breadth.

Emotion Regulation Choice in Internet Addiction: Less Reappraisal, Lower Frontal Alpha Asymmetry.

Individuals with internet addiction (IA) show difficulties in emotion regulation. However, they could effectively employ emotion regulation strategies when instructed. We speculate that this discrepancy might be caused by maladaptive emotion regulation choices.

Distinct neural-behavioral correspondence within face processing and attention networks for the composite face effect.

The composite face effect (CFE) is recognized as a hallmark for holistic face processing, but our knowledge remains sparse about its cognitive and neural loci. Using functional magnetic resonance imaging with independent localizer and complete composite face task, we here investigated its neural-behavioral correspondence within face processing and attention networks. Complementing classical comparisons, we adopted a dimensional reduction approach to explore the core cognitive constructs of the behavioral CFE measurement.

Erythroid nuclear dysplasia is associated with inferior outcomes for patients with myelodysplastic syndrome undergoing allogeneic hematopoietic cell transplantation.

Disease burden prior to hematopoietic cell transplantation (HCT) is difficult to assess in myelodysplastic syndrome (MDS), particularly in patients without excess blasts. We assessed whether morphologic dysplasia at the time of transplant can be a metric of disease burden that is associated with post-transplant outcomes in MDS patients. We identified 84 MDS patients undergoing allogeneic HCT at our institution between 2010 and 2017 who received a bone marrow evaluation immediately prior to HCT.

Circulating miRNA in Patients Undergoing Total Pancreatectomy and Islet Autotransplantation.

Circulating microRNAs (miRNAs) can be biomarkers for diagnosis and progression of several pathophysiological conditions. In a cohort undergoing total pancreatectomy with islet autotransplantation (TPIAT) from the multicenter Prospective Observational Study of TPIAT (POST), we investigated associations between a panel of circulating miRNAs (hsa-miR-375, hsa-miR-29b-3p, hsa-miR-148a-3p, hsa-miR-216a-5p, hsa-miR-320d, hsa-miR-200c, hsa-miR-125b, hsa-miR-7-5p, hsa-miR-221-3p, hsa-miR-122-5p) and patient, disease and islet-isolation characteristics. Plasma samples ( = 139) were collected before TPIAT and miRNA levels were measured by RTPCR.

Impulse Inhibition Ability With Methamphetamine Dependents Varies at Different Abstinence Stages.

The purpose of this study is to evaluate whether the impulse inhibition ability with methamphetamine dependents would vary at different abstinence stages. Sixty-three methamphetamine dependents, including 31 short-term (< 10 months) and 32 long-term (≥ 10 months) abstinence participants, were recruited for this study. In addition, 33 men were recruited as the healthy control (HC) group.

Gender Role, But Not Sex, Shapes Humans' Susceptibility to Emotion.

It is unknown whether the famous sex-related difference in emotion processing is accounted for by biological sex, gender role, or their interaction. To clarify the issue, in Study 1 we recorded event-related potentials in response to negative and positive images of diverse intensities when 47 masculine (26 males) and 47 feminine (22 males) subjects performed a non-emotional task. The occipital P1 and N1 amplitudes were larger in women than in men, while feminine subjects showed larger N1 amplitudes than masculine subjects, regardless of sex.

Emotion regulation by implementation intention is generalizable to unspecified situations: The nature of the underlying goal matters.

Implementation intentions (II), which specify how to respond in a given situation based on the goal, is known for its automaticity of regulating emotion to the specified situation. However, it is unknown whether such regulatory effects can be generalized to unspecified situations. For this purpose, we performed four experiments, each consisting of specified (bloody) and unspecified (non-bloody) stimuli with the goal of disgust (Exp.

Automatic Reappraisal-Based Implementation Intention Produces Early and Sustainable Emotion Regulation Effects: Event-Related Potential Evidence.

Implementation intention has proven effective in regulating intense emotions but is found to be difficult when instructed regulation is used. Here, we aim to test whether automatic reappraisal-based implementation intention (RII) downregulates intense negative emotion more efficiently than controlled reappraisal (CR) using a two-phase event-related potential (ERP) experiment. In the regulation phase, both RII and CR decreased subjective experiences of negative emotion relative to passive watching, irrespective of emotional intensity.

Benefits of Implicit Regulation of Instructed Fear: Evidence From Neuroimaging and Functional Connectivity.

Instructed fear, which denotes fearful emotions learned from others' verbal instructions, is an important form of fear acquisition in humans. Maladaptive instructed fear produces detrimental effects on health, but little is known about performing an efficient regulation of instructed fear and its underlying neural substrates. To address this question, 26 subjects performed an instructed fear task where emotional experiences and functional neuroimages were recorded during watching, explicit regulation (calmness imagination), and implicit regulation (calmness priming) conditions.