Association between coronary artery stenosis and myocardial injury in patients with acute pulmonary embolism: A case-control study.

Background: The potential impact of pre-existing coronary artery stenosis (CAS) on acute pulmonary embolism (PE) episodes remains underexplored. This study aimed to investigate the association between pre-existing CAS and the elevation of high-sensitivity cardiac troponin I (hs-cTnI) levels in patients with PE.

Methods: In this multicenter, prospective case-control study, 88 cases and 163 controls matched for age, sex, and study center were enrolled.

Research on the Flexural Performance of Steel Pipe Steel Slag Powder Ultra-High-Performance Concrete Components.

In order to study the flexural performance of the combined structure of steel-pipe and steel slag powder ultra-high-performance concrete (UHPC), nine round steel-pipe beams filled with steel slag powder UHPC of different types were fabricated according to the orthogonal test method with the steel pipe type, coarse aggregate content, steel fiber admixture, and curing system as parameters. The broken ring morphology, deformation characteristics, deflection distribution, and flexural bearing capacity of the steel-pipe-UHPC beams were analyzed via a pure bending test and a finite element simulation. The results show that the damage morphology of the round steel-tube-UHPC beams prepared by using steel slag powder UHPC as the inner filling material was "bow damage" under the pure bending load, and the load capacity was higher.

Vaccination against coronavirus disease 2019 in patients with pulmonary hypertension: A national prospective cohort study.

Background: Coronavirus disease 2019 (COVID-19) has potential risks for both clinically worsening pulmonary hypertension (PH) and increasing mortality. However, the data regarding the protective role of vaccination in this population are still lacking. This study aimed to assess the safety of approved vaccination for patients with PH.

Experimental animal models of pulmonary hypertension: Development and challenges.

Pulmonary hypertension (PH) is clinically divided into 5 major types, characterized by elevation in pulmonary arterial pressure (PAP) and pulmonary vascular resistance (PVR), finally leading to right heart failure and death. The pathogenesis of this arteriopathy remains unclear, leaving it impossible to target pulmonary vascular remodeling and reverse the deterioration of right ventricular (RV) function. Different animal models have been designed to reflect the complex mechanistic origins and pathology of PH, roughly divided into 4 categories according to the modeling methods: non-invasive models in vivo, invasive models in vivo, gene editing models, and multi-means joint modeling.

Radiological features combined with IDH1 status for predicting the survival outcome of glioblastoma patients.

Background: Radiological characteristics may reflect the biological features of brain tumors and may be associated with genetic alterations that occur in tumorigenesis. This study aimed to investigate the relationship between radiological features and IDH1 status as well as their predictive value for survival of glioblastoma patients.

Methods: The clinical information and MR images of 280 patients with histologically confirmed glioblastoma were retrospectively reviewed.