Publications by authors named "Jie-Ting Huang"
Nano-silicate platelets (NSP), an exfoliated product from natural clays, have been validated for biosafety and as an effective supplement to alleviate mycotoxicosis. Since NSP induced noticeable cell death, we therefore investigated further the mechanism of cytotoxicity caused by NSP. Exposure to NSP impaired membrane integrity and caused cell death in a dose-dependent manner.
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- The study investigates the role of NADPH oxidase 4 (NOX4) in neural tube defects (NTDs), focusing on its regulation by miR-322, which has been linked to increased apoptosis during neurulation.
- Using an all-trans-retinoic acid (ATRA)-induced mouse model and various assays, researchers confirm that miR-322 can inhibit NOX4 expression and its associated apoptotic effects.
- Findings suggest that the miR-322/NOX4 interaction is significant in reducing apoptosis during NTD formation, offering insights into potential therapeutic strategies for NTDs.
The efficacy of nanosilicate clay platelets (NSCP), exfoliated silicates from natural montmorillonites, as a feed additive for ameliorating fumonisin B1 (FB1) toxicosis was evaluated. Toxicological mechanisms by NSCP were examined through proteomic and biochemical analyses. Dietary supplementation with NSCP at a low level of 40 mg/kg of feed improved growth performances in chickens with respect to FB1 toxicosis.
View Article and Find Full Text PDFThe aim of this study was to investigate the effect of dietary supplementation of nanosize zinc on zinc digestibility, growth performances, immune response and serum parameters of weanling piglets. Ninety-six LYD weanling piglets were assigned to control, zinc oxide (ZnO), organic-Zn (Zn-methionine) and nanosize ZnO (nano-Zn) groups with four replicates. The zinc was at the 120 mg/kg level in the treatment group's diet, while the control group's was 80 mg/kg Zn.
View Article and Find Full Text PDF[Clinical features of Candida albicans sepsis in preterm infants: an analysis of 13 cases].
Zhongguo Dang Dai Er Ke Za Zhi
October 2012
Objective: To investigate the clinical features of Candida albicans sepsis in preterm infants.
Methods: Retrospective analysis was performed on the clinical data of 13 preterm infants with Candida albicans sepsis, who were born at 28 to 36 weeks of gestational age and who weighed between 1400 and 2815 g.
Results: The infants were infected with Candida albicans at the age of 19±11 d, with the main clinical manifestations being apnea, poor response, poor skin perfusion, blood oxygen concentration decrease, dark skin, yellowish skin, heart rate increase in the rest state, copious phlegm and difficulty in weaning from the ventilator.
[Bedside treatment of retinopathy of prematurity by laser photocoagulation].
Zhongguo Dang Dai Er Ke Za Zhi
September 2010
Objective: To study the efficacy of bedside treatment by laser photocoagulation for retinopathy of prematurity (ROP) in preterm infants hospitalized in the Neonatal Intensive Care Unit (NICU).
Methods: The clinical data of 30 cases of ROP who underwent peripheral laser ablation on bedside in the NICU from March to August 2009 were studied retrospectively.
Results: A total of 59 eyes from 30 patients received the laser therapy, with a total cure rate of 95%.