Publications by authors named "Jie-Shi Xie"
In vitro biological characterization of DCUN1D5 in DNA damage response.
Asian Pac J Cancer Prev
April 2013
Article Synopsis
- Novel biomarkers for laryngeal squamous cell carcinoma (LSCC) are urgently needed, leading to the identification of multiple associated genes using microarray expression profiling.
- The gene DCUN1D5 showed high expression in LSCCs, and its overexpression increased cell migration, invasion, and proliferation significantly in laboratory tests.
- After DNA damage, DCUN1D5 levels decreased, and reducing its expression led to less cell division and more cell death, suggesting it plays a critical role in the DNA damage response.