Publications by authors named "Jie-Hua Du"
Article Synopsis
- The study investigates how endometrial volume and flow parameters, along with serum CA125 levels, can help differentiate between benign and malignant endometrial lesions.
- It analyzed data from 250 patients, revealing that endometrial cancer (EC) patients had significantly thicker and larger endometrial volumes, as well as higher vascular flow parameters compared to those with benign lesions.
- The findings suggest that the vascular index (VI) is a more reliable indicator than endometrial thickness for distinguishing between benign and malignant cases, with elevated CA125 levels also correlating with cancer severity.
The present study discusses the expression and effect of the SOX17 gene in endometrioid adenocarcinoma. MTT assay is performed to determine the growth inhibition ratio of the DNA methyltransferase inhibitor 5-AZA for endometrial carcinoma cells, and the real-time fluorescence quantification PCR (qRT-PCR) was used to detect the mRNA expression of SOX17, β-catenin, and CyclinD1 in endometrial carcinoma tissues before and after using 5-AZA to treat the endometrial carcinoma cell line. There were 30 cases on endometrioid adenocarcinoma tissues and 10 cases on normal endometrial tissues.
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