Publications by authors named "Jie Nguyen"

Rationale And Objectives: Identifying underlying discoid morphology in the setting of a lateral meniscal tear (LMT) can be challenging with no clear consensus on its definition. We aim to determine the magnetic resonance imaging (MRI) characteristics of discoid morphology, including a novel meniscal height ratio.

Methods: A retrospective study of patients undergoing arthroscopic repair of isolated LMT between 2018 and 2023.

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Background: Trochlear dysplasia is a consistent risk factor for recurrent patellofemoral instability (PFI), but there is limited understanding of how the trochlea develops during growth. The aim of this study was to evaluate serial magnetic resonance imaging (MRI) studies performed in skeletally immature patients with and without PFI to characterize changes in trochlear anatomy over time.

Hypothesis: PFI leads to progressive worsening of trochlear dysplasia over time.

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Background: Osteoid osteomas are most commonly found in the femur and preferentially affect the pediatric population. Magnetic resonance imaging (MRI) findings of femoral osteoid osteomas are not well described.

Objective: To systematically characterize pretreatment MRI findings of clinically confirmed femur osteoid osteomas in children and determine location-dependent differences.

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Background: Osteochondritis dissecans (OCD) of the knee is a focal idiopathic alteration of subchondral bone and/or its precursor with risk for instability and disruption of adjacent cartilage. Treatment options focused on preventing premature osteoarthritis vary depending on multiple patient and lesion characteristics, including lesion mobility.

Purpose: To differentiate lesion mobility before arthroscopy using a multivariable model that includes patient demographic characteristics and physical examination findings.

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Article Synopsis
  • The study investigates how the structure and growth potential of the proximal tibia compares to the distal femur in children during their growth spurt using diffusion tensor imaging (DTI).
  • It involved 108 healthy children, analyzing DTI parameters like tract number, length, and volume, and finding that the proximal tibial tracts were more numerous in the central area while distal femoral tracts were more peripheral.
  • The results indicated that tibial tract volume was significant during peak height gain, showing that the tibia's growth patterns occur earlier than those of the femur.
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Article Synopsis
  • - The study examines how effective MRI is at identifying instability in osteochondritis dissecans (OCD) lesions in the medial femoral condyle of children, with data collected from 59 kids aged around 12.5 years who underwent knee MRIs between 2016 and 2023.
  • - Two radiologists reviewed MRI images to track various factors—like joint effusion and cartilage changes—to classify lesions as stable or unstable. The ultimate determination was based on results from arthroscopy or follow-up evaluations.
  • - Findings showed that while MRI's sensitivity and specificity varied by specific features, certain indicators (like skeletal maturity and cartilage alteration) had strong associations with instability, meaning they could help predict which lesions might require more
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Background: Discoid lateral meniscus (DLM) is the most common congenital abnormality of the meniscus. Tears are common; treatment is frequently not definitive, often requiring reoperation.

Purpose: To report the clinical manifestations, physical characteristics, operative treatments and findings, complications, and reoperations of DLM in pediatric patients from multiple centers across North America.

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Article Synopsis
  • Osteochondritis dissecans (OCD) affects the osteochondral junction, leading to unstable bone fragments and disrupted cartilage, causing chronic knee pain primarily in children and young adults.
  • The literature mostly discusses OCD in the medial femoral condyle (MFC), but unclear terminology related to patients' skeletal maturity complicates diagnosis and treatment options.
  • This article explores the MFC OCD's pathophysiology, the significance of imaging techniques, and includes a case study connecting imaging findings to the ROCK classification for better management of the condition.*
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  • The article discusses how the normal development of the knee joint in children can present imaging findings that may look like injuries or weaknesses, emphasizing the importance of understanding these variations.
  • It categorizes developmental variants into tibiofemoral and patellofemoral compartments, focusing on specific conditions and injuries that can occur in each area.
  • Additionally, the article highlights various soft tissue and bone structures that can also exhibit unique developmental characteristics, which can be easily confused with actual pathologies.
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The pediatric elbow is a complex joint that undergoes rapid growth and development. The normal anatomy of the elbow varies depending on the age of the patient, which can be challenging for imaging interpretation. This article reviews developmental variants and common pathologies of the pediatric elbow, with a focus on their radiologic features.

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Year-round participation in youth sport that involves high levels of repetitive movement fosters an environment in which overuse injuries are likely to occur. Epiphyseal primary physeal stress injuries (PSIs), unique to skeletally immature athletes, are a particular concern, given their potential for growth disturbance. Initially observed in Little League baseball players, these injuries are now known to affect the long bones around the shoulder, elbow, wrist, hand, knee, ankle, and foot of skeletally immature athletes involved in a variety of sport activities.

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Growth and maturation occur in a predictable pattern throughout the body and within each individual bone. In the appendicular skeleton, endochondral ossification predominates in long bones and growth plates. The ends of these long bones are sites of relative weakness in the immature skeleton and prone to injury from acute insult and overuse.

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Background: Despite representing over half of all pediatric patella fractures, inferior pole patellar sleeve fractures (PSFs) are a relatively uncommon pediatric injury. As a result, existing literature on PSFs is limited to case reports and small case series. The purpose of this study was to evaluate the radiographic and clinical characteristics of operatively treated PSFs as well as outcomes following surgical management.

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Background: Most healthcare providers utilize magnetic resonance imaging (MRI) to assist in diagnosing and treating osteochondritis dissecans (OCD) of the capitellum. However, consensus on imaging features that portend clinically relevant information in the care of these lesions has not been determined.

Purpose: To conduct a survey on the MRI features of a capitellar OCD that are salient for clinical decision-making using a classic Delphi protocol.

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Purpose: To examine the distribution and characteristics of pediatric foot fractures on radiographs with respect to age and skeletal maturation, and to identify predictors of surgery.

Methods: This retrospective study included children (≤ 18 years) with foot fractures, who underwent radiographic examinations (2020-2022). Electronic medical records were reviewed to obtain demographic and clinical data.

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Article Synopsis
  • - The study investigates how skeletal maturity affects the morphology and alignment of the patellofemoral joint in patients with patellar osteochondritis dissecans, highlighting that younger patients may heal better than those who are skeletally mature.
  • - MRI data from 68 children showed that most lesions were located on the central patella, with significant findings indicating abnormal angles and indices across the sample, particularly in skeletally mature knees.
  • - Skeletally mature patients displayed more severe morphological abnormalities (higher Dejour types) and less favorable alignment measurements compared to their immature counterparts, suggesting that age impacts the complexity of knee conditions.
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Increase in youth sports participation, longer duration of play, and earlier starting points have increased the prevalence of acute and repetitive overuse musculoskeletal injuries. This rise in injury rates has led to increased efforts to better understand the susceptible sites of injury that are unique to the growing immature skeleton. Upper extremity injuries are currently the best studied, particularly those that occur among pediatric baseball players and gymnasts.

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Youth soccer (football) is immensely popular internationally. Earlier participation, sport sub-specialization, and year-around practice have led to an increased incidence of injury from both acute trauma and repetitive overuse. The growth plates (physes) of the immature skeleton are particularly vulnerable to injury and delayed diagnosis can lead to future growth disturbance and long-term morbidity.

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Article Synopsis
  • The study examined knee MRI findings in symptomatic young soccer players to understand how skeletal maturity affects prevalence and surgery predictors.
  • Ninety-seven players were analyzed, showing that Osgood-Schlatter disease was more common in immature knees, while ACL injuries and meniscal tears were more prevalent in mature knees.
  • The presence of knee effusions, ACL injuries, and lateral meniscal tears were identified as key predictors for whether these players would need surgery, especially among those who were skeletally mature.
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Article Synopsis
  • The study investigates the presentation and treatment outcomes of patients with osteochondritis dissecans (OCD) lesions in the patella and trochlea, addressing previously limited research with small sample sizes.
  • Conducted at a single institution from 2008 to 2021, it included 68 patients and evaluated their return to sports, pain resolution, imaging results, and overall treatment success after a minimum follow-up of 12 months.
  • Results showed that while 62% of patients returned to sports and 54% experienced pain resolution, many still had lingering symptoms, indicating a need for improved treatment strategies for these conditions.
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Background: Elbow pain is common among youth baseball players and elbow MRI is increasingly utilized to complement the clinical assessment.

Objective: To characterize, according to skeletal maturity, findings on elbow MRI from symptomatic youth baseball players.

Materials And Methods: This IRB-approved, HIPAA-compliant retrospective study included pediatric (<18 years of age) baseball players with elbow pain who underwent MRI examinations between 2010 and 2021.

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The physis, or growth plate, is the primary structure responsible for longitudinal growth of the long bones. Diffusion tensor imaging (DTI) is a technique that depicts the anisotropic motion of water molecules, or diffusion. When diffusion is limited by cellular membranes, information on tissue microstructure can be acquired.

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Objective: To investigate the diagnostic accuracy and time in the detection of fractures on pediatric foot radiographs marked without and with localization cues.

Method: One-hundred randomly selected foot radiographic examinations that were performed on children (<18 years old) after injury and with at least 4 weeks of follow-up were included. Blinded to history and diagnosis, 4 readers (one each: medical student, pediatrician, pediatric orthopedic surgeon, and pediatric musculoskeletal radiologist) retrospectively and independently reviewed each examination twice (without and with cue, at least 1 month apart, and after randomization).

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Measurement of angles on foot radiographs is an important step in the evaluation of malalignment. The objective is to develop a CNN model to measure angles on radiographs, using radiologists' measurements as the reference standard. This IRB-approved retrospective study included 450 radiographs from 216 patients (< 3 years of age).

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