Chronic social defeat stress broadly inhibits gene expression in the peripheral taste system and alters taste responses in mice.

Human studies have linked stress exposure to unhealthy eating behavior. However, the mechanisms that drive stress-associated changes in eating behavior remain incompletely understood. The sense of taste plays important roles in food preference and intake.

An enhancer RNA-based risk model for prediction of bladder cancer prognosis.

Background: Bladder cancer patients have a high recurrence and poor survival rates worldwide. Early diagnosis and intervention are the cornerstones for favorable prognosis. However, commonly used predictive tools cannot meet clinical needs because of their insufficient accuracy.

A Method for Detecting the Randomness of Barkhausen Noise in a Material Fatigue Test Using Sensitivity and Uncertainty Analysis.

The magnetic Barkhausen noise (MBN) signal provides interesting clues about the evolution of microstructure of the magnetic material (internal stresses, level of degradation, etc.). This makes it widely used in non-destructive evaluation of ferromagnetic materials.

Catalyst-Free One-Step Preparation of Self-Crosslinked pH-Responsive Vesicles.

The fabrication of block copolymer (BCP) vesicles with controlled membrane permeability and promising stability remains a considerable challenge. Herein, a new type of pH-responsive and self-crosslinked vesicle based on a hydrolytically hindered urea bond is reported. This kind of vesicle is formed by the self-assembly of a pH-responsive and hydrolytically self-crosslinkable copolymer poly(ethylene glycol)-block-poly[2-(3-(tert-butyl)-3-ethylureido)ethyl methacrylate-co-2-(diethylamino)ethyl methacrylate] (PEG-b-P(TBEU-co-DEA)).

Tunable and Processable Shape-Memory Materials Based on Solvent-Free, Catalyst-Free Polycondensation between Formaldehyde and Diamine at Room Temperature.

Compared with traditional thermosets, malleable thermosets have more applications in aerospace, biotechnology, and construction. Here we report a one-step, solvent-free, catalyst-free polycondensation method between diamine and formaldehyde to prepare a series of malleable hemiaminal dynamic covalent networks (HDCNs). The materials have excellent malleability and reprocessability by hot pressing.

An Enzyme-Responsive "Turn-on" Fluorescence Polymeric Superamphiphile as a Potential Visualizable Phosphate Prodrug Delivery Vehicle.

The development of inexpensive and highly efficient enzyme-responsive polymers has significantly contributed to targeted drug delivery systems. Here, a superamphiphile with a capability of fluorescent dissociation sensing is designed. It is constructed with negatively charged adenosine 5'-triphosphate (ATP) and negatively charged fluorescein diphosphate (FDP), which are used as fluorescence detection, and a cationic diblock copolymer methoxy-poly(ethylene glycol) -b-poly(2-dimethyl-aminoethyl methacrylate) .