Publications by authors named "Jichen Xie"
Comparison of drug-eluting bead transarterial chemoembolization combined with apatinib versus drug-eluting bead transarterial chemoembolization for the treatment of unresectable hepatocellular carcinoma: a randomized, prospective, multicenter phase III trial.
Signal Transduct Target Ther
November 2024
Article Synopsis
- A phase III trial involving 12 centers in China compared the effectiveness of drug-eluting bead transarterial chemoembolization (DEB-TACE) combined with apatinib against DEB-TACE alone for patients with unresectable hepatocellular carcinoma (uHCC).
- The results showed that the combination treatment led to significantly better progression-free survival (7.1 months vs. 5.2 months) and overall survival (23.3 months vs. 18.9 months), along with higher response rates and disease control.
- Most treatment-related adverse events were mild, although there were some increased risks of side effects such as hypertension and fatigue associated with the combination therapy, which still had an overall favorable safety profile
Magnetic resonance lymphography findings across different clinical stages of lower limb lymphedema.
J Plast Reconstr Aesthet Surg
September 2024
Objective: To investigate the findings on lower limb lymphedema using magnetic resonance lymphography (MRL).
Methods: MRL was used to record the lymphatic vessel morphology, distribution of lymphatic vessels, dermal backflow (DBF), and morphology of inguinal lymph nodes in 112 patients (175 affected limbs) with lower limb lymphedema at different clinical stages (according to the International Society of Lymphology staging criteria 2020).
Results: The lymphatic vessel morphology significantly differed at different clinical stages (X =59.
is an important opportunistic pathogen that causes a variety of infections. It is critical for bacteria to maintain metal homeostasis during infection. By using an isogenic deletion mutant of strain NTUH-K2044, we found that MntP was a manganese efflux pump.
View Article and Find Full Text PDFBackground: The evidence of transcatheter arterial chemoembolization (TACE) plus tyrosine kinase inhibitor and immune checkpoint inhibitor in unresectable hepatocellular carcinoma (HCC) was limited. This study aimed to evaluate the role of TACE plus apatinib (TACE + A) and TACE combined with apatinib plus camrelizumab (TACE + AC) in patients with unresectable HCC.
Methods: This study retrospectively reviewed patients with unresectable HCC who received TACE + A or TACE + AC in 20 centers of China from January 1, 2019 to June 31, 2021.
Klebsiella pneumoniae is a leading cause of severe infections in humans and animals, and the emergence of multidrug-resistant strains highlights the need to develop effective vaccines for preventing such infections. Live attenuated vaccines are attractive vaccine candidates available in the veterinary field. We recently characterized that the K.
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