Publications by authors named "Jibran A Khan"

Article Synopsis
  • AI is becoming crucial in thoracic surgery, improving outcomes through accurate diagnosis of conditions like non-small-cell lung cancer and lymph node metastasis.
  • Applications of AI, including machine learning and natural language processing, enhance robotic-assisted surgeries and perioperative management, boosting surgical precision and patient safety.
  • Despite its benefits, challenges like data privacy, biases, and ethical issues need to be addressed, with this manuscript reviewing the current state and future directions of AI in the field.
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Article Synopsis
  • Intraoperative measurements for positioning the acetabular cup were taken using both fluoroscopy and a navigation system during surgery.
  • A specific technique involved using a C-arm at a 40° angle to capture an anteroposterior view and align the fluoroscopy beam with the cup's orientation.
  • The study found strong agreement between the two measurement methods, highlighting fluoroscopy as a reliable alternative in surgeries where navigation systems are unavailable.
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Lung cancer remains a global health concern, with non-small cell lung cancer (NSCLC) comprising the majority of cases. Early detection of lung cancer has led to an increased number of cases identified in the earlier stages of NSCLC. This required the revaluation of the NSCLC treatment approaches for early stage NSCLC.

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Neutrophils are the most abundant of the circulating immune cells and are the first to be recruited to sites of inflammation. Neutrophils are a heterogeneous group of immune cells from which are derived extracellular traps (NETs), reactive oxygen species, cytokines, chemokines, immunomodulatory factors, and alarmins that regulate the recruitment and phenotypes of neutrophils, macrophages, dendritic cells, T cells, and B cells. In addition, cytokine-stimulated neutrophils can express class II major histocompatibility complex and the internal machinery necessary for successful antigen presentation to memory CD4 T cells.

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Background: Chronic subdural hematoma (CSDH) is a frequently encountered neurosurgical disease among the elderly. The mainstay treatment involves surgical evacuation, but recurrence rates of approximately 13% pose complications. Adjuvant treatments, including tranexamic acid (TXA), have been explored, yet consensus on their efficacy and safety in elderly patients remains uncertain.

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Aneurysmal bone cysts (ABCs) are non-neoplastic primary bone tumors, typically involving the long bones and vertebrae in the first 2 decades of life. ABCs require prompt diagnosis and intervention due to their rapidly expansile nature and ability to destroy the adjacent normal bone. ABCs rarely affect the rib.

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This report describes the unique case of an intra-articular lipoma in a 34-year-old male. The patient presented with a history of chronic knee pain associated with an intermittent sensation of the knee giving way. Physical examination and initial radiographic imaging were unremarkable.

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Functional characterization of metagenomic DNA often involves expressing heterologous DNA in genetically tractable microorganisms such as Escherichia coli. Functional expression of heterologous genes can suffer from limitations due to the lack of recognition of foreign promoters or presence of intrinsic terminators on foreign DNA between a vector-based promoter and the transcription start site. Anti-terminator proteins are a possible solution to overcome this limitation.

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