Publications by authors named "Jiazheng Miao"
Article Synopsis
- Culture-independent 16S rRNA gene metabarcoding is used for microbiome profiling, but accurate estimates require accounting for the number of 16S rRNA gene copies (16S GCN) in different organisms.
- The new method ANNA16 utilizes deep learning to predict 16S GCN values directly from gene sequences, showing improved performance over existing prediction tools based on a large dataset.
- ANNA16's ability to identify key positions in gene sequences without prior phylogenetic knowledge opens up possibilities for applications beyond just 16S GCN prediction.
The emergence of antibacterial resistance (ABR) is an urgent and complex public health challenge worldwide. Antibiotic resistant genes (ARGs) are considered as a new pollutant by the WHO because of their wide distribution and emerging prevalence. The role of environmental factors in developing ARGs in bacterial populations is still poorly understood.
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