[Study on the CFHR1 level and its genetic polymorphisms in type 2 diabetes mellitus patients].

Objective: To explore the characteristics in CFHR1 concentration and the frequency of CFHR1 gene polymorphisms of patients with type 2 diabetes mellitus (T2DM) based on the high level of complement factor H (CFH) expression among such patients and the similarity between CFHR1 and CFH in terms of sequence and functions.

Methods: Fifty T2DM patients and 30 healthy controls were selected. The plasma samples were separated by pI with OFFGEL electrophoresis following solution digestion.

[Body composition investigation of 2321 Shenzhen government and enterprise staffs].

Objective: To understand the laws of human body composition change and the status of the overweight and obesity of government and enterprise staffs.

Methods: In July 2013 - January 2014, 2321 adults more than 20-year-old healthy check-up crowd with complete human body composition and height as well as weight data in a medical center in Shenzhen were collected by convenience sampling method.

Results: The overweight rates of male and female were 46.

[Snacks consumption among residents in Shenzhen City].

Objective: To describe the status of snacks consumption among residents in Shenzhen.

Methods: By a multiple stage probability proportionate to size sampling, 12 communities were randomly selected from 8 districts of Shenzhen based on population proportion. In the second stage, 30 households were randomly selected from each community.

[The distribution of 24 elements in urine from Shenzhen residents].

Objective: This study aims to describe the distribution of 24 elements in urine of Shenzhen residents.

Methods: According to the principle of equal probability of selection method, in March 2011 to July, total 11 communities were chosen as the basic sampling unit in Shenzhen, with 1 to 2 communities in each of the municipal district. Then 75 families from each sampling unit were selected using systematic sampling method.

Environmental lead pollution threatens the children living in the Pearl River Delta region, China.

Introduction And Purpose: The objective of this study is to determine children's blood lead levels and identify sources of lead exposure. Childhood lead exposure constitutes a major pediatric health problem today in China. A blood lead screening survey program for children in the age group of 2-12 years residing in Pearl River Delta region, south of China, was carried out from Dec 2007 to Jan 2008.

[Nutrition survey on the collective in Shenzhen public institution].

Objective: Nutrition survey on the collective who performs light physical activity.

Methods: Based on weighing records and two-months energy intake, combined with the Chinese Dietary Guidelines and Chinese Dietary Recommended Nutrient Intake (RNI), 45 healthy volunteers were chosen to evaluate their current nutrient status.

Results: The dietary structure of the collective was simple and unreasonable.

[Basic metabolic rate of young adults in Shenzhen].

Objective: To measure the basic metabolic rate (BMR) of young adults with normal BMI in Shenzhen.

Methods: 25 men and 25 women in hospital were selected according to questionnaire, medical examination, blood test, liver function, nephron function, thyroid gland level, and TSH. Their BMR and resting metabolic rate (RMR) were measured by using the K4b2 in normal circumstances.

Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial.

Unlabelled: Chronic hepatitis B and its life-threatening sequelae are highly prevalent in China. There is a need for effective new therapies to suppress hepatitis B virus (HBV) replication and ameliorate liver disease. In this study, we compared the efficacy of telbivudine, a nucleoside analogue, with lamivudine in Chinese patients.

[The degree of HBV suppression with 24 week telbivudine- or lamivudine-treatment in hepatitis B patients predicts the efficacy of the treatment at week 52].

Objectives: To investigate the possibilities of an association between the degrees of HBV suppression with nucleoside treatments at week 24 and week 52 in hepatitis B patients and to find a useful predictor for treatment efficacy.

Methods: In this phase III, double-blind, multicenter trial, we compared the efficacy of telbivudine treatment with lamivudine treatment in 332 Chinese compensated chronic hepatitis B patients. The patients were randomly assigned to a daily 600 mg telbivudine treatment group or daily 100 mg lamivudine group for 24 weeks.

Effects of lipopolysaccharides stimulated Kupffer cells on activation of rat hepatic stellate cells.

Aim: To study the effects of Kupffer cell-conditioned medium (KCCM) derived from lipopolysaccharide (LPS) treatment on proliferation of rat hepatic stellate cells (HSC).

Methods: HSC and Kupffer cells were isolated from the liver of Wistar rats by in situ perfusion with pronase and collagenase and density gradient centrifugation with Nycodenz and cultured. KCCM was prepared and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) colorimetric assay was used to detect HSC proliferation.